Ch. 22: Respiratory System part 2 Flashcards

1
Q

Pulmonary ventilation (breathing) consist of two phases:

A

Inspiration( breathing in)

Expiration (breathing out)

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2
Q

List the 3 Pressures

A
Atmospheric pressure 760 mmhg
Intrapulmonary pressure (alveoli, equalizes with atm
Intrapleural pressure( pleural cavity, always negative)
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3
Q

Intrapleural cavity is always negative due to

A

lungs natural tendency to recoil

surface tension of alveolar fluid

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4
Q

Atelectasis ( lung collapse) occurs due to

A

Plugged bronchioles - collapse of alveoli
Wound that admits air into pleural cavity (pneumothorax)
Lack of surfactant

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5
Q

__________, Pressure is inversely proportional to Volume, P increase, V decrease

A

Boyle’s law

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6
Q

Inhalation: effects on diaphragm and intercoastal muscles and pressure

A

Pressure: decreases Volume: increases
Diaphragm: contracts Intercoastal muscles: contracts

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7
Q

During inhalation the pressure in the lungs are ____ than the atmospheric pressure

A

lower

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8
Q

The 3 physical factors influencing breathing are

A

Lung compliance, air resistance and alveolar surface tension

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9
Q

_______ is the major nonelastic source of resistance to gas flow

A

Friction

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10
Q

The relationship between flow (F), pressure (P), and resistance (R) is:

A

F= P/R
Change of pressure and Resistance
Gas flow inversely with resistance

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11
Q

Factors that decrease air resistance are:

A

Epinephrine and Antihistamines dilates bronchioles and reduces air resistance

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12
Q

Function of surfactant:

A

Reduces surface tension of alveolar fluid and discourages alveolar collapse

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13
Q

Define lung compliance

A

measure of the change in lung volume that occurs with a change in transpulmonary pressure.

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14
Q

Lung compliance is diminished by:

A

Nonelastic scar tissue (fibrosis)
Reduced production of surfactant
Decreased flexibility of the thoracic cage

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15
Q

___________, pulmonary gas exchange, capillary – alveoli

A

External respiration

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16
Q

three factors that influence external respiration

A

thickness and surface area of the respiratory membrane
partial pressure gradients and gas solubilities
ventilation( amount of gas reaching the alveoli) and perfusion ( blood flow in pulmonary)

17
Q

_________, normal breathing

A

tidal volume

18
Q

_______, maximum air you can inhale

A

inspiratory reserve volume

19
Q

__________, forcefully exhale out

A

expiratory reserve volume

20
Q

____________, air remaining in the lungs

A

Residual volume

21
Q

_________, inspired air fills the conducting respiratory passageways and never contributes to gas exchange in the alveoli

A

DEAD SPACE

22
Q

___________ involves capillary gas exchange in body tissues

A

Internal respiration

23
Q

Oxygen transport is carried in two ways

A

Bound to hemoglobin (98.5%)

Dissolved in Plasma (1.5%)

24
Q

Each hemoglobin molecules can bind to _ oxygen molecules

A

4

25
Q

When 1-3 oxygen molecules are bound to a hemoglobin molecule, they refer as

A

partial saturated

26
Q

When 4 oxygen molecules bound to hemoglobin molecule, they refer as

A

fully saturated

27
Q

The rate at which Hb reversibly binds or releases O2 is regulated by

A

P02 and Pco2
temperature
blood pH

28
Q

Increases in temperature, H+, Pco2, and BPG lead to

A

Enhance O2 unloading

29
Q

Inadequate O2 delivery to tissues

A

Hypoxia

30
Q
Abnormal or too little Hb
Blocked circulation
Metabolic poisons
Pulmonary disease
Carbon monoxide
A

Anemic
Ischemic (stagnant)
Histotoxic
Hypoxemic

31
Q

Carbon dioxide transport 3 ways:

A

Dissolved in plasma: 7-10%
Chemically bound to hemoglobin: 20%
As bicarbonate ions in plasma: 70%

32
Q

___________, an enzyme that reversibly catalyzes the conversion of carbon dioxide and water to carbonic acid

A

carbonic anhydrase

33
Q

__________ and _____ are the main controllers of the regulation of breathing

A

medulla oblongata, and pons

34
Q

___________, sensors responding to the changing levels of co2, o2 and h+ in arterial blood

A

chemoreceptors

35
Q

______ is the most potent and most closely controlled, as well as the most powerful respiratory stimulant

A

CO2

36
Q

An adaptive response to high altitudes

A

Acclimatization

37
Q

___________, distinguished by destruction of alveolar walls, and permanent enlargement of the alveoli

A

emphysema

38
Q

________, inhaled irritants lead to chronic production of excessive mucus, obstruct airways, impaling breathing and gas exchange

A

Chronis bronchitis

39
Q

__________ , infectious disease caused by the bacterium Myobacterium tuberculosis

A

Tuberculosis