ch. 18 smart book missed questions Flashcards
which term refers to the production of blood especially the formed elements
hematopoiesis
where are the first hemopoietic tissues in the human embryo found
yolk sac
Which term refers to clusters of stem cells that form in the yolk sac, then migrate into the embryo to colonize the liver, spleen, thymus and bone marrow?
Blood islands
Hemopoietic stem cells in the bone marrow give rise to colony forming units, which in turn give rise to what?
Formed elements
One molecule of hemoglobin contains which of the following?
4 globin chains and 4 heme groups
Choose all the clinical measurements that express the blood’s ability to carry oxygen.
RBC count
hemoglobin concentration
hematocrit
Red blood cells rely on anaerobic fermentation to produce ATP because they lack the organelle called
mitochondria
Which organ produces erythrocytes in the fetus, but only produces lymphocytes in the adult?
Spleen
Name the protein that binds oxygen and buffers blood pH.
Hemoglobin
How many heme groups are there in each hemoglobin molecule?
4
Erythropoietin is secreted by the
kidneys
The hematocrit and hemoglobin concentration are clinical data that describe which of the following?
The amount of oxygen the blood can carry
The process of erythropoiesis normally takes how many days?
3-5
List, in order, the stages of erythropoiesis. Start with the least differentiated cell type at the top and end with erythrocytes.
- hemopoietic stem cells
- colony-forming units
- erythoblasts
- reticulocytes
- erthrocytes
Under normal circumstances only 0.5 - 1.5% of the circulating blood cells are reticulocytes. Which medical condition might cause this number to increase?
Excessive blood loss
Hypoxemia, resulting from hemorrhage, high altitude, or emphysema, may stimulate which of the following?
erythropoiesis
What is the role of erythropoietin?
Stimulates RBC production
Hypoxemia can occur transiently, but it is always associated with disease conditions.
false
Which cell in the production of a red blood cell leaves the bone marrow to enter the blood?
Reticulocyte
Hypoxemia triggers the production of erythropoietin. Erythropoietin increased the rate of erythropoiesis. This an example of which of the following?
Negative feedback control
Which protein transports iron in the blood?
Transferrin
Choose all that are causes of hypoxemia.
Abrupt increases in activity level
COPD
Emphysema