Casus 45 Flashcards

1
Q

Je bent huisarts en je hebt bij een 67-jarige mannelijke patiënt diabetes mellitus type 2 gediagnostiseerd.

A
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2
Q

metformine effect

A

(eerste keus)
- remt gluconeogenese
- verhoogt insulinegevoeligheid van perifere weefsels

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3
Q

metformine bijwerkingen

A
  • maag-darmklachten
  • misselijkheid
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4
Q

sulfonylureum effect

A
  • stimuleert insulineafgifte door betacellen
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5
Q

sulfonylureum bijwerkingen

A
  • gewichtstoename
  • hypoglycemie
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6
Q

SGLT2-remmer effect

A
  • verhoogt glucose uitscheiding door glucoseresorptie in nieren te remmen
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7
Q

SGLT2-remmer bijwerkingen

A
  • genitale infecties
  • polyurie
  • gunstig effect op bloeddruk en gewicht
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8
Q

GLP1-agonist effect

A
  • stimuleert insulineafgifte
  • remt maaglediging en glucagon
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9
Q

GLP1-agonist bijwerkingen

A
  • maag-darmklachten
  • braken
  • diarree
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10
Q
A
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