Autoimmune Disease 2 Flashcards

1
Q

Examples of molecular mimicry?

A

Autoimmune haemolysis after mycoplasma pneumoniae, i antigen homologous to red blood cell antigens

Rheumatic fever, streptococcal infection

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2
Q

T1D prevalence?

A

0.8%, rising by 5% ever year

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3
Q

By the time you develop diabetes what percent of pancreas is destroyed?

A

90%

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4
Q

HLA alleles for type 1 diabetes?

A

DR3 and DR4

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5
Q

What could be a possible cause of T1D?

A

Coxsackie virus, causes pancreatitis and precipitate autoimmune diabetes

Protein 2C has homologous with islet cell antigen glutamic acid decarboxylase

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6
Q

LUPUS signs?

A
Butterfly rash
Photosensitivity
Hives
Serositis, pulmonary fibrosis
Joint pain
Autoimmune cytopenia
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