Approach to secondary skin infection Flashcards

1
Q

What presenting sign would a bacterial infection have?

A
  • Pustules
  • Crust
  • Scale
  • Alopecia
  • Variable pruritus
  • Nodules (if deep infection)
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2
Q

What presenting signs would Malassezia have?

A
  • Scale +++
  • Variable pruritus
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3
Q

What is the most common commensal bacteria + fungi?

A

*Staph. pseudintermedius
*Malassezia pachydermatis

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4
Q

What are underlying diseases for commensal skin infections?

A

*Allergy e.g., cAD
* Ectoparasites
* Self trauma
– pain
* Other infections
- dermatophytosis
- leishmaniasis
* Immune deficiency
– endocrinopathy
– chemotherapy
– drug induced
* Keratinisation defects
* Follicular dysplasia
* Environment / hygiene issues
* Anatomical defects
* Metabolic disease
* Iatrogenic
- post-grooming (Pseudomonas)
- maceration
* Neoplasia

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5
Q

What bacteria cause pyoderma?

A
  • Staphylococcus pseudintermedius
    – most common
  • S. aureus, S. schleiferi and S. canis
    – less common
  • Gram-negative or atypical bacteria
    – E.g., E. coli, Proteus spp., Pseudomonas spp.
    – uncommon to rare
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6
Q

What is an example of primary skin pathogens?

A

*Dermatophytes

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7
Q

Bacterial pyoderma can be classified on the depth of infection, what are the 3 classes?

A

1.Surface
– Superficial epidermis
– Overgrowth NOT infection as NOT pyogenic
2. Superficial
– Epidermis and hair follicles
3. Deep
– Epidermis, hair follicles, dermis +/- subcutaneous fat

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8
Q

What are the clinical presentations for surface infection?

A
  1. ‘Hotspots’ = pyotraumatic dermatitis (PTD)
  2. Skin fold pyoderma = intertrigo
  3. Bacterial overgrowth (ddx Malassezia dermatitis) common in dogs with cAD (atopic dermatitis)
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9
Q

What are hotspot/pyotraumatic dermatitis?
What breeds are predisposed?

A
  • Lesions develop within hours due to self-trauma
  • Underlying allergy (FAD) or pruritic/painful trigger
  • Rottweiler, Golden Retriever & GSD predisposed
  • Lesions usually on cheek, neck or rump
  • Well-demarcated flat eroded moist lesion with erythematous halo
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10
Q

How does intertrigo form?

A
  • Compromised barrier
  • friction, altered micro-climate, loss of normal ventilation and/or accumulation of fluids
  • Microbes proliferate, produce toxins & create inflammation
  • May have concurrent skin disorder e.g., canine atopic dermatitis
    – may progress to superficial or deep infection
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11
Q

Malassezia dermatitis is uncommon in cats - what are the predisposed breeds?

A

Devon rex
Sphinx
Persian

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12
Q

What dog breeds are predisposed to Malassezia dermatitis?

A

Basset hounds
West highland white terrier
Cocker spaniels

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13
Q

What is malassezia dermatitis a secondary disease in?

A

– Thymoma-induced exfoliative dermatitis
– Paraneoplastic alopecia
– FIV or FeLV
– Feline allergy

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14
Q

What are the clinical signs of malassezia dermatitis?

A
  • Seborrhoeic dermatitis in Devon Rex and Sphynx
    – paronychia with brown nails
  • Otitis
  • Keratinisation disorders
    – e.g., chin acne, idiopathic facial dermatitis of Persians
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15
Q

What condition is seen at the superficial depth?

A

*Superficial folliculitis
-usually staphylococci

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16
Q

What are the clinical signs of superficial pyoderma?

A

Erythema, follicular papules & pustules, crusts, epidermal collarettes,
erosions & hyperpigmented macules

17
Q

What condition is found at the 3rd depth?

A

*Deep pyoderma
-folliculitis + furunculosis

18
Q

What are the clinical signs of deep pyoderma?

A
  • Heat
    *swelling
    *erythema
    *furuncles
    *nodules
    *bullae
    *plaques
    *sinus tracts
    *ulcers
    *exudation
    *crusts
19
Q

How are pyodermas diagnosed?

A

– Direct impression smear (DIS)
– Cotton tip/swab smear (IDS)
– Adhesive tape strip (ATS)
– Fine needle aspirate (FNA)

20
Q

How would you take a culture with superficial infections?

A

– rupture and sample intact lesion if present
– sample erosion under a crust or at the edge of a collarette

21
Q

How would you take a culture with deep infections?

A

– fresh tissue sample (biopsy)
– rupture intact lesion if possible and use swab (not if suspect mycobacteria)
– swab into deep sinus tract (last resort)