9/7/12 pt. III

Question 1

Does the trachea deviate toward or away from the affected lung in a large pleural effusion?`

Answer 1

away

Question 2

Does the trachea deviate toward or away from the affected lung in atelectasis?

Answer 2

toward

Question 3

Name 2 drugs that can cause seizures.

Answer 3

Bupoprione
Isoniazid
Imipenem

Question 4

Pick’s disease affects what area of the brain?

Answer 4

frontal cortex

Question 5

Where in the cell is transketolase found? What pathway is it involved with?

Answer 5

cytoplasm; pentose phosphate

Question 6

What is the defective protein in hypertrophic cardiomyopathy?

Answer 6

beta-myosin heavy chain, a cardiac sarcomere protein

Question 7

Injury to what blood vessel is likely to occur in fracture of the neck of the femur and may cause avascular necrosis?

Answer 7

medial circumflex a.

Question 8

Wilson’s disease causes cystic degeneration of what area of the brain?

Answer 8

putamen

Question 9

Where can you see the caudate nucleus in a coronal section of the cortex?

Answer 9

lateral to ventricles, supero-medial to internal capsule

Question 10

What is the most common manifestation of CMV infection in the immunocompetent adult?

Answer 10

mono

Question 11

What is the most common manifestation of CMV infection in an HIV pt?

Answer 11

retinitis

Question 12

Which TB drug works best intracellularly?

Answer 12

pyrazinamide

Question 13

Nevirapine, efavirenz, and delavirdine are all …

Answer 13

non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Question 14

Dofetilide, which may be used for pharmacological cardioversion, is what kind of anti-arrhythmic?

Answer 14

Class III - slows K+ rectifier current

Question 15

What is pituitary apoplexy?

Answer 15

hemorrhage into a pre-existing pituitary adenoma

Question 16

How does the tetrodotoxin block the action potential?

Answer 16

binds closed Na+ channels, preventing depolarization

Question 17

peptostreptococcus and fusobacterium may be found where in the normal adult?

Answer 17

oral flora

Question 18

What is chlorpheniramine?

Answer 18

first gen H1 receptor antagonist (like diphenhydramine)

Question 19

What do jistological specimens of HAV infected livers look like?

Answer 19

ballooning degeneration of hepatocytes, mononuclear infiltrates, and Councilman bodies (eosinophilic, apoptotic hepatocytes)

Question 20

Middle-aged male w/ chronic GI upset, greasy stools, weight loss, joint pain, and PAS+ macrophage infiltrate in lamina propria of intestine. Dx?

Answer 20

Tropheryma whippelii

Question 21

Amphotericin B and Nystatin inhibit fungal growth by?

Answer 21

binding ergosterol in cell membrane

Question 22

What system converts pro-carcinogens to carcinogens?

Answer 22

CYP450

Question 23

What two organ systems does Kaposi’s sarcoma affect?

Answer 23

Skin and GI

Question 24

What cardiac pathology causes an S4?

Answer 24

decreased LV wall compliance