9/10/12

Question 1

What is the primary target of nitroglycerin? What is the primary effect on the CV system?

Answer 1

dilates large veins; reduces preload

Question 2

What is prazosin?

Answer 2

alpha-1 antagonist

Question 3

What is the primary target and effect of nifedipine?

Answer 3

dilates small arteries/arterioles; reduces afterload

Question 4

Which subtype of AML can present with persistent infection and coagulopathy with hemorrhage?

Answer 4

Acute Promyelocytic Leukemia (APL or AML M3)

Question 5

What is the translocation in APL?

Answer 5

t(15;17)

Question 6

What is the standard initial treatment for APL?

Answer 6

all-trans retinoic acid + anthracycline

Question 7

What is raltegravir?

Answer 7

an HIV inTEGRAse inhibitor

Question 8

What inherited disease causes bilateral acoustic neuromas?

Answer 8

NF-2

Question 9

Why does vWF deficiency lead to an increased PTT?

Answer 9

vWF serves as a carrier for factor VIII –> functional factor VII deficiency

Question 10

What is a comedocarcinoma of the breast?

Answer 10

a subtype of ductal carcinoma in situ (DCIS)

Question 11

What is the most common type of benign liver tumor?

Answer 11

cavernous hemangioma