8/24/12 Flashcards

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1
Q

What nerve is typically injured as it passes under the hook of the hamate?

A

ulnar

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2
Q

What histopathological findings would be present in the adrenal cortex of a person with Conn’s syndrome?

A

hyperTROPHY of the zona glomerulosa

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3
Q

What histopathological findings would be present in the adrenal cortex of a person with Cushing’s?

A

hyperPLASIA of the zona fasciculata

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4
Q

What histopathological findings would be present in the adrenal cortex of a person with Addison’s disease?

A

cortical atrophy

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5
Q

What is the VOMIT pathway?

A

Val, Odd-chain FA’s, Methionine, Ile, and Thr are all catabolized to propionyl CoA, which can be further metabolized to methylmalonyl-CoA and then to Succinyl-CoA for the Kreb’s cycle.

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6
Q

What cofactor is required by propionyl CoA carboxylase?

A

biotin

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7
Q

What co factor is required by methylmalonyl-CoA isomerase?

A

B12

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8
Q

What are the 2 main etiologies for lacunar infarcts?

A

lipohyalinosis and microatheroma of the penetrating vessels.

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9
Q

In which disease would you see pink areas in the white matter of the brain? What are these pink areas?

A

MS - oligodendrocyte apoptosis

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10
Q

What is the etiology of paraneoplastic cerebellar degeneration?

A

autoantibodies against Purkinje cells

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11
Q

Newborn: small for gestational age w/ bilateral cleft lip, microcephaly, microphthalmos, and rocker-bottom feet. Dx? Genetic abnormality?

A

Patau syndrome; trisomy 13

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12
Q

Newborn w/ prominent occiput, low-set ears, clenched fists in a characteristic manner. May have malrotation of the gut and/or Meckel’s diverticulum. Dx?

A

Edward’s syndrome, trisomy 18

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13
Q

Where does most lipid absorption occur?

A

jejunum

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14
Q

Where is bile reabsorbed to the enterohepatic circulation?

A

ileum

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15
Q

What nerves provide motor innervation to the tongue? How is it divided?

A

Hypoglossal n. provides motor innervation to all mm. of tongue, except the palatoglossus, which is innervated by the vagus n.

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16
Q

What provides general sensory innervation to the anterior 2/3 of the tongue?

A

V3 of trigeminal n.

17
Q

What provides general sensory innervation to the posterior 1/3 of the tongue?

A

glossopharyngeal n.

18
Q

What nerve provides general sensory innervation to the very back part of the tongue?

A

Vagus n.

19
Q

What provides gustatory innervation to the anterior 2/3 of the tongue?

A

Chorda tympani (CN VII)

20
Q

What provides gustatory innervation to the posterior 1/3 of the tongue?

A

glossopharyngeal n.

21
Q

What provides gustatory innervation to the root of the tongue, larynx and upper esophagus?

A

Vagus n.

22
Q

What drugs would be appropriate for a schizophrenic with apathy, decreased emotional range, and poverty of speech?

A

Atypical anti-psychotics such as Clozapine, Olanzapine, Risperidone, and Quetiapine.
(If your schizophrenic is being too QUIET, give him QUIETapine.)

23
Q

Why can a patient rapidly recover from thiopental administration (~30 mins)?

A

redistribution into fat tissues

24
Q

A professional runner (or morbidly obese pt) presents with pain at the medial aspect of the knee, especially when climbing stairs. What structure is likely inflamed?

A

(pes) anserine bursa

25
Q

Child presents w/ skin rash, colicky abdominal pain, polyarthralgia, and vascular lesions w/ C3 and IgA deposition. Dx?

A

Henoch-Schonlein Purpura

26
Q

A pt w/ diabetic neuropathy develops urinary retention. What drug may have caused this side effect?

A

Amitriptaline or any other TCA w/ anti-muscarinic effects (e.g. imipramine, doxepin)

27
Q

Which antibiotic binds to D-ala-D-ala peptidoglycan precursors to inhibit cell wall formation?

A

Vancomycin