9/16/12 b

Question 1

What artery travels with the radial nerve through the spiral groove?

Answer 1

DEEP brachial artery

Question 2

What artery is likely to be damaged in a supracondylar fracture?

Answer 2

brachial artery

Question 3

What sort of maneuvers would increase the systolic murmur that may be heard in hypertrophic cardiomyopathy?

Answer 3

those that decrease venous return to the heart, such as Valsalva.

Question 4

What parasympathetic innervation does the facial nerve provide?

Answer 4

lacrimal, submandibular, and sublingual salivary

Question 5

What is an essential activator of Carbamoyl Phosphate synthetase I?

Answer 5

N-acetylglutamate

Question 6

What skeletal abnormalities come w/ Friedreich’s ataxia?

Answer 6

kyphoscoliosis and pes cavus

Question 7

In Friedreich’s ataxia, degeneration of what neural structures causes gait ataxia?

Answer 7

spinocerebellar tracts (ascending & descending)

Question 8

I Friedreich’s ataxia, degeneration of what neural structures causes loss of position and vibration sense?

Answer 8

dorsal columns AND dorsal root ganglia

Question 9

What endocrine disorder develops in about 10% of pts w/ Friedreich’s ataxia?

Answer 9

DM

Question 10

What is the main mechanism of action of streptokinase?

Answer 10

activates plasminogen, which cleaves fibrin

Question 11

What are 2 possible side effects of streptokinase?

Answer 11

hemorrhage and hypersensitivity

Question 12

What is the standard triple therapy for H. pylori infection?

Answer 12

1 week: PPI, clarithromycin, amoxacillin

Question 13

What bacteria is ciproifloxacin most effective against?

Answer 13

Gram (-) aerobic rods such as P. aeruginosa and Legionella

Question 14

What is the mechanism of angioedema - swelling of face, tongue, larynx, etc - in some cases of ACE-I therapy?

Answer 14

Bradykinin accumulation

Question 15

What is vascular medial calcinosis? Effects?

Answer 15

medial calcification of muscular arteries in older people; no Sx

Question 16

What is the most common cause of aortic stenosis?

Answer 16

degenerative (senile) calcification

Question 17

What is the effect of aortic stenosis on the carotid pulse?

Answer 17

Pulsus parvus et tardus

reflects diamond-shaped murmur

Question 18

What sort of valvular problem does cystic medial necrosis of the aorta predispose to?

Answer 18

aortic regurgitation following aortic dissection

Question 19

Hemophilia B is d/t a deficiency of what clotting factor?

Answer 19

IX

Question 20

What is Laplace’s law? (Relates distending pressure of a sphere to radius.)

Answer 20

P=2T/r

where T = surface tension

Question 21

According to Laplace’s law, which kind of a sphere is more likely to collapse, one with a large radius or one with a small radius?

Answer 21

small

Question 22

What is the most common cause of nephrotic syndrome in adults? It is associated with a “spike-and-dome” pattern on EM.

Answer 22

Membranous glomerulopathy

Question 23

What GI disease causes alternating diarrhea and constipation and possibly fistulas?

Answer 23

Crohn’s disease