9/5/12 Flashcards
What cells secrete renin?
modified smooth muscle cells of afferent arteriole
What condition affecting the bones causes an increase in unmineralized osteoid and widened osteoid seams?
Vit D def (rickets/osteomalacia)
Paget’s disease is most commonly seen in what age group?
elderly
What is the effect of moderate constriction of the efferent arteriole on GFR? On FF?
both up (at higher degrees of constriction, the gfr will decrease)
What is the level of the first porion of the duodenum?
L1
A tumor in the 3rd part of the duodenum puts which structures at greateest risk?
uncinate process of pancreas, SMA, and SMV.
Shaken baby syndrome, like head trauma in an elderly person, can cause what kind of an intracranial hemorrhage?
SUBdural
Ticlopidine (ADP antagonist anti-plt drug) may rarely cause mouth ulcers. What serious side effect does this indicate?
neutropenia
What is the target od Abciximab (anti-plt drug)?
GpIIb/IIIa
What is the effect of uremia on bleeding time? PT? PTT?
prolonged; normal; normal
What is the most common cause of a new heart murmur in a young patient?
Bacterial endocarditis
What is argatroban? What is its primary use?
direct thrombin inhibitor; tx and prophylaxis of heparin-induced thrombocytopenia (HIT) (including percutaneous intervention
How may heparin affect blood counts?
thrombocytopenia
What is a side effect of abciximab and other GpIIb/IIIa inhibitors?
thrombocytopenia
How does dialysis improve platelet function?
It removes anti-plt factors.
