9/23/12 Flashcards

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1
Q

Which 2 bacteria secrete toxins that inactivate the 60S ribosomal subunit?

A

Shigella and EHEC

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1
Q

The neurons of the CNS, neurohypophysis, retina, pineal gland, preganglionic autonomic fibers, astrocytes, ependymal cells, and choroid plexus are all derived from what embryonic structure?

A

Neurectoderm

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1
Q

What is the only major vestige of the notochord in humans?

A

nucleus pulposus of the intervertebral disks

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1
Q

What conditions are associated w/ Cheyne-Stokes breathing?

A

cardiac and neurologic disease (esp. advanced CHF)

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2
Q

What is the pattern Cheyne-Stokes breathing? What drives this pattern?

A

Increasing/decreseasing tidal volumes followed by periods of apnea. Delayed response to PaCO2.

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3
Q

How does ezetimibe lower LDL levels?

A

inhibits intestinal absorption of cholesterol

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4
Q

What dyslipidemia is associated with an increased risk of pancreatitis?

A

hyperTRIGLYCERIDEmia

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5
Q

What is the most common type of lung cancer in women and non-smokers?

A

adenocarcinoma

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6
Q

Which type of lung cancer is associated with Cushing’s, SIADH, and Lambert-Eaton syndrome, again?

A

small cell carcinoma

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7
Q

Where does squamous cell carcinoma of the lung usually arise?

A

On larger bronchi at areas of squamous metaplasia.

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8
Q

Which kind of lung tumor is described histologically: Large polygonal cells that form solid sheets or nests. Usu. located peripherally.

A

large cell carc

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9
Q

How do right-sided colon cancers usu. present clinically?

A

intestinal obstruction

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10
Q

How do left-sided colon cancers usu. present?

A

Fe-def anemia; anorexia, wt. loss, and/or malaise

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