6.3 Digestion and Absorption of Carbs Flashcards
What is the order of carb digestion?
- Mouth: Salivary amylase breaks starch
- Stomach: HCL acid deactivates amylase (no more carb digestion)
- Small intestine: Pancreatic amylase + brush-border enzymes secrete carb digesting enzymes like lactase (di to mono saccharides)
- Large intestine: Undigested carbs broken down by bacteria
- Excreted
We can only absorb _________ sugars
monosaccharide
How is sugar absorbed in the small intestine?
We need a protein transporter on both sides of the cell via active transport (needs ATP)
What is lactose intolerance caused by?
Insufficient secretion of the enzyme lactase. This means bacteria in the large intestine ferment the lactose to make methane.
What are some symptoms of being lactose intolerant?
Cramps, bloating, diarrhea, and abdominal pain
Once sugars are absorbed into the blood, a ______ response occurs
glycemic
What is a glycemic response?
Spike on blood glucose that follows a meal once glucose enters the general circulation
What are diets that cause a lower glycemic response associated with?
Lower risk of type 2 diabetes, CVD, and obesity
What is the glycemic index?
A relative ranking of a food’s potential to spike blood sugar on a 100-point scale (glucose scores 100)
Which is better, glycemic index or load? Why?
Load, is it takes into account how much carbs is actually in the food
How does our body regulate blood glucose so it doesn’t stay too high (maintains glucose homeostasis)?
Insulin and glucagon (increases sugar) are secreted by the pancreas
What can imbalanced blood glucose cause?
Hypoglycemia (low blood glucose, affects energy levels)
Hyperglycemia (high blood glucose, can lead to diabetes if chronic)
What is the endocrine function of the pancreas?
Secrete insulin and glucagon (increases sugar) into the blood
What is the exocrine function of the pancreas?
Secrete pancreatic juices into the digestive tract for digestion
How does glucagon increase blood glucose?
- Glycogenolysis: Convert glycogen into glucose
- Gluconeogenesis: Convert amino acids into glucose
- Lipolysis: Breakdown stored lipids. Glycerol from triglycerides can be used to make glucose