20 December Flashcards
What is ruxolitinib?
A kinase inhibitor used for myelofibrosis, polycythaemia vera or graft-versus-host disease
What is myelofibrosis?
Myelofibrosis is an uncommon type of bone marrow cancer that disrupts your body’s normal production of blood cells. Myelofibrosis causes extensive scarring in your bone marrow, leading to severe anemia that can cause weakness and fatigue
What is polycythaemia vera?
A type of blood cancer in which the bone marrow produces too many red blood cells, thickening the blood, increasing the risk of blood clots.
What is graft-versus-host disease?
A condition that occurs when donor bone marrow or stem cells attack the recipient.
Describe the role of opioid suppositories.
Suppositories have slower onset and longer effect than conventional tablets; they may be useful for patients unable to swallow
What is eltrombopag?
A thrombopoietin receptor agonist which increases platelet production
