Aldosterone Antagonists/Potassium-Sparing Diuretics/Mineralocorticoid Receptor Antagonists

Question 1

Name 2 Aldosterone Antagonists.

Answer 1

1. Eplerenone

2. Spironolactone

Question 2

What is the indication of spironolactone as per Medication Profiler?

Answer 2

To remove excess fluid from the body and reduce potassium loss (Mild diuretic)

Question 3

What does the “other important information” section on MedProfiler say about spironolactone?

Answer 3

Best taken with food to avoid stomach upset.
This medicine can reduce the blood pressure, and can sometimes cause dizziness early in the course of treatment. Rise slowly from a sitting or lying position to prevent dizziness occurring.
This medicine may also cause stomach upset, nausea, diarrhoea, leg cramps and may cause breast soreness or an increase in breast size.

Question 4

What does the “generic subheading” section on MedProfiler say about spironolactone?

Answer 4

Take with or soon after food