Zyprexa (Olanazapine) Flashcards
1
Q
Drug Classification
A
Antipsychotic
2
Q
Mechanism of Action
A
SSRI, NE Reuptake inhibitor ->antipsychotic and Anticholinergic effect
3
Q
Pharmacokinetics
A
Onset of Action- <30 minutes
Peak Effects- 6 hours
Duration of Effects- varies
Half-Life- 21-54 hours
4
Q
Indications/Field Use
A
- Acute psychosis or agitation
- Alzheimer’s disease
5
Q
Contraindications
A
Hypersensitivity
6
Q
Side Effects/Adverse Reactions
A
Myalgia(muscle pain), somnolence(drowsiness), dizziness, tremors, tachycardia, orthostatic hypotension, nausea, dry mouth
7
Q
Dose
A
Adult:
10mg IM
Pedi:
Not Established
8
Q
Precautions
A
- Cautions in pts with CV disease, predisposition for hypotension and Parkinson’s disease
- Must be reconstituted in 3mL sterile water prior to administration
9
Q
Drug-Drug Interaction
A
Potentiates hypotension effects of anti-hypertensives
