Ipratropium Bromide (Atrovent) Flashcards
1
Q
Drug classification
A
Anticholinergic/parasympatholytic
2
Q
Mechanism of action
A
Muscarinic ACh receptor antagonist-> inhibits parasympathetic stimulation in bronchial smooth muscle cells, submucosal glands and goblet cells-> dries respiratory tract secretions and allows for bronchodilation
3
Q
Pharmacokinetics
Onset of action
Peak effects
Duration of effects
Half-life
A
- Onset of action- varies
- Peak effects- 1.5-2 hours
- Duration of effects- 4-6 hours
- Half-life- 1.5-2 hours
4
Q
Indications/field use
A
- Respiratory distress and wheezing associated with bronchial asthma.
- reversible bronchospasm associated with COPD
5
Q
Contraindications
A
- Hypersensitivity
- Hypersensitivity to atropine
6
Q
Side effects/adverse reactions
A
Anxiety, HA, palpitations, dizziness, nervousness, rash, dry mouth, N&V
7
Q
Dose
A
Small volume nebulizer Adult/Pedi:
500 micrograms/0.5 mg
8
Q
Precautions
A
Typically administered with a Beta agonist
9
Q
Drug-drug interactions
A
None EMS
