Nitrous Oxide (Nitronix, Entonox) Flashcards
1
Q
Drug Classification
A
Analgesic/Anesthetic Gas
2
Q
Mechanism of Action
A
NMDA (Glutamate)-R antagonist ->blockade of neuronal signals to the conscious mind from other parts of the brain, creating dissociative anesthesia, euphoria, and analgesia
3
Q
Pharmacokinetics
A
- Onset of Action- 2-5 minutes
- Peak Effects- 2-5 minutes
- Duration of Effects- 2-5 minutes
- Half-Life- 5 minutes
4
Q
Indications/Field Use
A
- Acute musculoskeletal pain
- Pain associated with burns
- Ischemic chest pain
5
Q
Contraindications
A
- AMS secondary to drugs, alcohol or head injury
- Inability to comprehend verbal instructions
- Patient with COPD, abdominal pain/distention, or thoracic injury suspicious for pneumothorax
- Facial Trauma
6
Q
Side Effects/Adverse Reactions
A
AMS, Dizziness/light-headedness, hallucinations, N&V
7
Q
Dose
A
Adult:
50/50 mixture oxygen and nitrous oxide- self-administered until the pt notes relief or drops the mask
8
Q
Precautions
A
- Use only in well ventilated area
- May be impossible to administer in temperatures less than 21 degrees F
9
Q
Drug-Drug Interactions
A
May potentiate other CNS depressants including narcotics, sedatives, hypnotics,and alcohol
