Acetaminophen (Tylenol) Flashcards

1
Q

Drug Classification

A

Antipyretic/Analgesic

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2
Q

Mechanism of Action

A

COX inhibitor ->elevation of pain threshold, antipyretic by action on hypothalamic heat regulatory center

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3
Q

Pharmacokinetics

A
  • Onset of Action- 15-30 minutes
  • Peak Effects- 30-120 minutes
  • Duration of Effects- 3-4 hours
  • Half-Life- 1-3 hours
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4
Q

Indications/Field Use

A

Pediatric Fever

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5
Q

Contraindications

A

Hypersensitivity

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6
Q

Side Effects/Adverse Reactions

A

Abdominal pain, dizziness, hypoglycemia, N&V

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7
Q

Dose

A

Pedi:

15mg/kg PO q 4-6 hours PRN, max dose 4g/day

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8
Q

Precautions

A
  • Metabolized by liver- overdose can be toxic
  • Doesn’t have anti-platelet aggregation effect
  • Doesn’t have peripheral anti-inflammatory effects
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9
Q

Drug-Drug Interactions

A

Chronic excessive use of alcohol increases risk of hepatotoxicity

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10
Q

Toxic Dose

A

140mg/kg

Cut in half if pt has liver issues

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