Etomidate (Amidate) Flashcards
1
Q
Drug Classification
A
Sedative/Hypnotic
2
Q
Mechanism of Action
A
Depresses reticular activating system of the brain and potentiates GABA
-> causes sedation
3
Q
Pharmacokinetics
A
- Onset of Action- 10-20sec
- Peak Effects- <1min
- Duration of Effects- 3-5min
- Half-Life- 30-70min
4
Q
Indications/Field Use
A
Induction Agent for RSI
5
Q
Contraindications
A
Hypersensitivity
6
Q
Side Effects/Adverse Reactions
A
Myoclonic skeletal muscle movement, apnea, hyperventilation/hypoventilation, laryngospasm, HTN/hypotension, Bradycardia/tachycardia, N&V
7
Q
Dose
A
Adult:
0.3mg/kg IV/IO over 15-30 seconds
Pedi:
0.3mg/kg IV/IO over 15-30 seconds
8
Q
Precautions
A
Consider alternate sedative in patients with severe asthma
9
Q
Drug-Drug Interactions
A
May prolong respiratory depression and apnea with Verapamil
