Week 8: Chp 30 Valvular Disease Flashcards
Risk Factors Of Valvular Disease
- increases with age
- infectious diseases such as infective endocarditis (IE), rheumatic fever, myocardial infarction, heart failure, congenital defects, and degenerative changes
- pregnancy increases risk of valvular disease because of the increased workload on the heart
- patients with risk factors for coronary artery disease are also at risk for valvular disease
Most common valvular diseases
-aortic stenosis and
-mitral regurgitation
>the least common valves affected are the tricuspid and pulmonic valves because of the low-pressure system in the right heart
Several types of Valvular Disease
- stenosis
- insufficiency or regurgitation
- prolapse
Regurgitation
backward flow through the valve
In response to backward flow through the valve, regurgitation, or resistance to forward flow through the constricted or stenosed valve what develops?
signs of right or left sided Heart failure
Mitral Valve regurgitation
causes backward flow of blood into the left atrium
-the increased blood volume raises the pressure in the atrium and pulmonary vessels and results in pulmonary edema and left sided heart failure
Aortic Valve Stenosis
obstructs the flow of blood from the left ventricle (LV), causing increased LV pressure
- left ventricle hypertrophy occurs to generate adequate force to open the valve
- over-time the left ventricle fails, also resulting in the signs of left sided heart failure
What happens in insufficiency of the tricuspid valve?
causes backward flow and increased pressure in the right atrium, which results in signs of right-sided heart failure such as JVD, generalized edema and ascites
Types of Valvular disease: Stenosis
stiffening and thickening of the valve leaflets, caused by calcium deposits or scarring, narrow the opening and obstruct flow
Types of Valvular Disease: Regurgitation or Insufficiency
blood flows or leaks backward- ventricle to atria, aorta to left ventricle, pulmonic circulation to the right ventricle– because of incomplete closing of the valve
Types of Valvular Disease: Prolapse
valve leaflets bulge backwards and do not close, causing regurgitation
First clinical sign of valvular disease
auscultation of a murmur
- a murmur can be a result of a high rate of blood flow through a valve, forward blood flow through a narrowed valve (stenosis), or backward blood flow through an incompetent valve (regurgitation)
- a cardiac murmur can be classified as systolic, diastolic, or continuous on the basis of where in the cardiac cycle it is best heard
Cardiac Murmurs can be classified how?
systolic, diastolic, or continuous on the basis of where in the cardiac cycle it is best heard
Cardiac murmurs classification: Systolic murmurs
can be heard during S1 or lub when the ventricles are contracting
- during this time the aortic or pulmonic valves should be open, and the mitral and tricuspid valves should be closed
- can be heard with aortic or pulmonic stenosis or mitral or tricuspid regurgitation
Cardiac Murmurs classification: Diastolic murmurs
can be heard during S2 or dub, when the ventricles are relaxing and the heart is filling
- the mitral and tricuspid valves should be open to allow for ventricular filling, and the aortic and pulmonic valves should be closed
- can be heard with aortic and pulmonic valve regurgitation or mitral and tricuspid stenosis
Clinical Manifestations of valvular disease
- SOB, dyspnea, orthopnea
- crackles
- angina
- syncope, dizziness
- dysrhythmias
- palpitations
- fatigue
- weight gain
- edema
- cool, pale extremities with weak pulses
Diagnostic Tests
- Echocardiogram to identify valve abnormalities and ejection fraction
- Chest x-ray to identify left or right heart hypertrophy and pulmonary edema
- Stress Testing: to identify functional capacity
- Heart Catheterization as a definitive test for stenosis done prior to corrective surgery
- CT or MRI
Diagnostic Tests
- Echocardiogram to identify valve abnormalities and ejection fraction
- Chest x-ray to identify left or right heart hypertrophy and pulmonary edema
- Stress Testing: to identify functional capacity
- Heart Catheterization: as a definitive test for stenosis done prior to corrective surgery
- CT or MRI
Medication Management
for valvular disease is dependent on the etiology and degree of the disease
- valvular disease with infectious etiology require antimicrobial therapy, whereas advanced valvular diseases require general HF management
- determined by the type of valve utilized in valve replacement; patients who undergo valve replacement with a mechanical prosthetic valve will need to be anticoagulated for life to prevent thrombotic events such as strokes
- Tissue valves have recommended anticoagulation for only 6 months after placement but have less longevity (typically considered in patients who are older or cannot be anticoagulated0
Medications
general HF management:
- angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), or angiotensin receptor-neprilysin inhibitors (ARNIs) with beta blockers to reduce heart rate and blood pressure
- Diuretics to decrease preload and pulmonary congestion
Safety Alert
care must be taken when managing blood pressure for patients with aortic stenosis
- these patients require higher preload in order to generate adequate pressure for blood flow through the stenosed valve
- decreasing preload can lead to decreased cardiac output and hypotension