Antilipemic: Antisense Oligonnucleotide Flashcards
1
Q
Common meds
A
Mipomersen
2
Q
Action
A
Lower LDL, total cholesterol, and apolipoprotein B
3
Q
Therapeutic use
A
Patients with homozygous familial hypocholesteremia
4
Q
Complications
A
Liver toxicity, hypertension, flu-like symptoms, and musculoskeletal pain
5
Q
Nursing considerations
A
- baseline AST, ALT, alkaline phosphate, total bilirubin and continue to monitor
- avoid alcohol and monitor for S+S
- monitor BP
- report flu-like symptoms or musculoskeletal pain
- given SQ weekly
