Week 6: Antihistamine Intranasal: Upper Respiratory Med Flashcards

1
Q

Antihistamine Intranasal Drug

A

azelastine

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2
Q

Expected Pharmacologic Action

A
  • work on the H2 receptor blocking histamine release in the small blood vessels, capillaries, and nerves during allergic reactions
  • relieve itching, sneezing, and rhinorrhea
  • do not relieve nasal congestion
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3
Q

Therapeutic Use

A
  • allergic reactions
  • anaphylaxis
  • motion sickness
  • insomnia
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4
Q

Complications

A
  • GI discomfort

- acute toxicity, excitation, hallucinations, incoordination, and seizures in children

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5
Q

Contraindications

A
  • pregnancy risk category B
  • contraindicated during third trimester of pregnancy, breastfeeding, and newborns
  • children and older adults
  • in asthma, seizure disorder, cardiac disease, renal disease, urinary retention, open-angle glaucoma, hypertension, prostate hypertrophy
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6
Q

Interactions

A

CNS depressants/ alcohol cause additive CNS depression

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7
Q

Medication Administration

A

-take with food

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8
Q

Nursing Interventions

A
  • administer activated charcoal and cathartic to decrease absorption of antihistamine
  • acetaminophen for fever
  • apply ice packs or sponge baths
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9
Q

Client Education

A

-avoid alcohol and medications causing CNS depression

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10
Q

Evaluation of Medication Effectiveness

A
  • improvement of allergic reaction (absence of rhinitis, urticaria)
  • relief of motion sickness (decreased nausea and vomiting)
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