Bipolar Flashcards
Mania
a distinct period during which mood is abnormally and persistently elevated, expansive, or irritable
Mania Includes:
-inflated self-esteem or grandiosity; decreased sleep; excessive and pressured speech, flight of ideas, distractibility, increased activity or psychomotor agitation and excessive involvement in pleasure seeking or risk taking activities with high potential for painful consequences
Mania: Mood
- excessively cheerful, enthusiastic, and expansive, or person may be irritable, especially when he/she is told no or has rules to follow
- often denies any problems, placing the blame on others for any difficulties he/she experiences
- some exhibit delusions or hallucinations in manic episodes
Hypomania
period of abnormally persistently devoted, expansive, or irritable mood and some milder symptoms of mania
-does not impair persons ability to function (may be productive) and have no psychotic features (delusions or hallucinations)
Mixed Episode
is diagnosed when person experiences both mania and depression nearly everyday for at least 1 week (rapid cycling)
Bipolar I
one or more manic or mixed episodes usually accompanied by major depressive episodes
Bipolar II
one or more major depressive episodes accompanied by at least one hypomanic episode
Bipolar Disorder
- involves extreme mood swings from episodes of mania to episodes of depression
- an alteration in mood that may be expressed by feelings of elation, inflated self-esteem, grandiosity, hyperactivity, agitation, racing thoughts, and accelerated speech
- mania can occur as part of the psychiatric disorder
Etiology
- excess of serotonin seen in mania
- excess of norepinephrine. this catecholamine energized the body
Diagnostic Work Up
- thyroid and other metabolic function studies suggest hyperexcitability
- lithium levels are measured
- renal studies: lithium is nephrotoxic
- sodium levels; lithium is a salt and needs sodium levels at appropriate range to transport lithium ions
- sodium levels below 120 mEq are dangerous to all but especially on lithium
- normal sodium range= 135-145 mEq
- serum chloride levels 95-105
Manic Phase
euphoric, grandiose, energetic, and sleepless
-poor judgment and rapid thoughts, actions, and speech
Depressed Phases
mood, behavior, and thought are the same as in people diagnosed with major depression
Onset and Clinical Course
- occurs in teens, 20s, 30s
- begin suddenly with rapid escalation of symptoms over a few days, and last from a few weeks to several months
- tend to be brief and end more suddenly than depressive episodes
Psychopharmacology
- life-time regimen of treatments
- anti-manic agent; Lithium
- anti-convulsant as mood stabilizers
- if a client experiences psychosis as well, anti-psychotics can be used in addition to bipolar med
Lithium
- salt contained in the human body
- treats bipolar mania and bipolar depression
- can stabilize bipolar disorder by reducing the degree and frequency of cycling or eliminating manic episodes
- competes for salt receptor sites, but also affects calcium, potassium, and magnesium ions as well as glucose metabolism
Lithium Action
work in the synapses to hasten destruction of catecholamines (dopamine, norepinephrine), inhibit neurotransmitter release, and decrease the sensitivity of post-synaptic receptors
-crosses blood brain barrier and placenta and is distributed in sweat and breast milk; not recommended during pregnancy
Anti-Convulsant Drugs
-used for clients who do not respond or have difficulty taking lithium because of side effects, problems with treatment regimen, drug interactions, or medical conditions such as renal disease that contraindicates use of lithium
Examples of Anti-Convulsant Drugs
- Divalproex
- Carbamazepine
- Lamotrigine
- Gabapentin
Anti-Convulsant: Divalproex (valproic acid)
used for simple absence and mixed seizures, migraine prophylaxis, and mania
- therapeutic levels are monitored
- baseline and ongoing liver function tests, including serum ammonia levels and platelet and bleeding times