Week 6: Laryngeal Cancer (Upper Respiratory Disorder) Flashcards
Where does Laryngeal Cancer Originate?
originates from the squamous cell that line the larynx and hypopharynx, the part of the pharynx behind the larynx, the entrance to the esophagus
How does Laryngeal Cancer Develop?
changes in the squamous cells from irritation, usually from heavy alcohol drinking and smoking, result in the squamous cells becoming precancerous
Clinical Manifestations
- hoarseness
- change in the voice that does not go away in 2 weeks (lower-than-usual pitch and raspy and hoarse sounds)
- persistent sore throat
- constant cough
- pain with swallowing
- ear pain that does not go away
- difficulty swallowing
- trouble breathing
- a lump or mass in the neck
- weight loss due to difficulty eating
Diagnosis
- starts with completion of a thorough health history (general health information, other medical conditions, onset of symptoms, risk factors, and family history)
- physical examination (neck, thyroid, lymph nodes, and muscle movement of the neck can indicate if tumor growth has invaded these structures)
- endoscopy and imaging
- laryngoscopy
- barium swallow, chest x-ray, CT, MRI, PET scans
Diagnosis Procedures
- health history and physical exam
- endoscopy and imaging (barium swallow, laryngoscopy, chest x-ray, CT, MRI, PET)
Laryngoscopy
allows for assessment of vocal folds and glottis for the presence of ulcerations, nodules, polyps, strictures, bleeding, or tumors
-may also be performed under general anesthesia, at which samples for biopsies are obtained if needed
Barium swallow
evaluates the throat and ability to swallow
Chest x-rays for?
obtained to evaluate the lungs for presence of lung cancer
CT, MRI, and PET scans are completed for?
to determine the presence of metastasis into the surrounding and distant soft tissues and for regional adenopathy, or lymph node involvement
Information Obtained through biopsy and diagnostic imaging
is used for determining the stage of the tumor and disease progression
How to determine the stage of cancer
based on size of the tumor, the involvement of the lymph nodes, and whether the cancer has spread to other sites within the body
Treatment is based off of?
- stage of disease
- location and size of the tumor
- whether the tumor is a reoccurrence
Treatment
- radiation therapy
- surgery
- chemotherapy
Radiation Therapy
used to eliminate cancer cells and maintain the structure and function of the larynx
-used to treat small tumors, reduce tumor size prior to surgery, or in patients unable to undergo surgery
Side Effects of Radiation Therapy
increased hoarseness, prolonged tissue healing, sore throat, difficulty swallowing, and if salivary glands are involved, dry mouth (xerostomia)