Antilipemics: HMG-CoA reductase inhibitors

Question 1

common meds

Answer 1

-statins

Atorvastatin

Question 2

Action of HMG-CoA reductase inhibitors

Answer 2

• decrease manufacture of LDL and VLDL

- increase manufacture of HDL

Question 3

Therapeutic use

Answer 3

hypercholesteremia

Question 4

Complications

Answer 4

hepatotoxicity and myopathy

Question 5

Nursing Considerations

Answer 5

• baseline liver function tests and CK and continue to monitor
• avoid alcohol, monitor for S+S of liver dysfunction
• take with evening meals