Week 11 lecture 20 biowarfare Flashcards

1
Q

In the history of bio warfare, what happened in the 1300s?

A

Siege of kaffa where mongols threw ppl with plague over wall

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2
Q

What was a regulation attempt to stop bio and chemical warfare?

A

the 1925 Geneva protocol

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3
Q

The geneva protocol still is upheld T/F?

A

FAlse; tjhere was not a way in place to keep it in check

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4
Q

The issue wityh the Dachau facility was?

A

bioweapons testsed against innocent ppl uring WWII

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5
Q

The issue with the Dachau facility and Gruinard island was?

A

bioweapons tested against innocent ppl during WWII

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6
Q

What type of bioweapon was used in Gruinard island?

A

Anthrax warfare

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7
Q

What did the bioweapons program from Japan do during WWII?

A

Contaminated Chinese cities’ water and food supply

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8
Q

Why is Fort Detrick , MD special?

A

That is where the biowarfare program was initiated in the USA. There were large scale anthrax weapons + defensive research

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9
Q

The anthrax outbreak in the USSR was in which lab?

A

tularemia lab

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10
Q

What was the frst and largest USA bioterror attack?

A

Rajneeshee Cult in the USA

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11
Q

The Rajneeshee cult spread what where in the US?

A

salmonella in Portland, OR, USA

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12
Q

What are the levels of the War on Terror in the USA? What is the highest risk?

A

A B and C; A

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13
Q

___ Prohibits the development, production, acquisition, transfer,
stockpiling and use of biological / toxin weapons & WMDs
* Signed by nearly all countries (183)
* Review conferences held every 5 years
* Again, no clear mechanisms to enforce the treaty exist.

A

United Nations (UN) Biological & Toxin Weapons Convention

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14
Q

Steps to mass produce bioweapons

A

Procure the agent, have skill for storage/handling, develop transmission (experts and money basically)

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15
Q

What is the best (worst for people’s survival) way to spread a bioweapon?

A

Aerosol transmission

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16
Q

Smallpox
Anthrax
Plague
Botulism
Tularemia
Viral hemorrhagic fevers (Ebola)
are which categories and whY>

A

A; not easy treatment/vaccination

17
Q

Weaknesses of smallpox as a weapon are?

A

only in 2 locations in world, easy diagnosis, available vaccine

18
Q

The most likely bioweapon to be used is? Why?

A

anthrax; easily found in nature and causes severe disease

19
Q

Weaknesses of anthrax as a weapon are?

A

Susceptible to major antibiotics
Antitoxin available (stockpiled)
Vaccine effective

20
Q

among the types of anthrax which is most deadly? Why?

A

Inhalational, leads to septicemia and respiratory failure

21
Q

Anthrax is not able to spread from person to person T/F?

22
Q

Weaknesses of plague as a weapon are?

A

treated with antibiotics and doesnot survive for long

23
Q

The most potent category A bioweapon toxin by weight

A

Botulinum Neurotoxin (BoNT)

24
Q

Weaknesses ofbotulism as a weapon are?

A

There is an antitoxin treatment available and stocked, and vaccine is not approved but is developed

25
Tularemia is also called ___ because that isthe reservoir
rabbit fever
26
How is tularermia spread?
inhalation of contaminated dusts or aerosols (NOT direct person to person)
27
Tularemia Disease causes what complications?
respiratory, pneumonic and systemic infection * 7% mortality in untreated cases
28
Positives of ebola as a bioweapon are?
it is easy to spread person to person and has high mortality with no cure
29
Weaknesses of ebola as a weapon are?
Ebola is unstable and hard to grow lots of. Plus a vaccine does exist for it
30
Transmission from Inhaled barnyard dust Dirt with feces, urine, placenta, milk Resistant to drying and very stable Can be carried long distanced by wind what am i describing an d wat category bioweapon is this?
Q fwever; B category
31
Weaknesses of Q fever as a bioweapon are?
low mortality/virulence and treatable and vaccine available
32
Weaknesses of Ricin toxin as a bioweapon are?
Can't spread person to person
33
What type of categoy of disease is foot and mouth disease?
Category C and livestock bioterrorism
34
What type of category of disease is foot and mouth disease?
Category C and livestock bioterrorism that would cause food sthortage and economic prioblems
35
What type of category of disease is foot and mouth disease?
Category C and livestock bioterrorism that would cause food shortage and economic problems
36
Highly toxic toxin extracted from the castor bean Grown at home, difficult to limit/regulate * Can be in form of powder, mist, pellet, dissolved in water, etc * Transmission by injection, oral ingestion, inhalation Similar symptoms as anthrax except no antidote * Fever, nausea, organ failure, pneumonia, shock * Supportive care only Has been used/attempted as a weapon MANY times What am I describing and what category is it?
Ricin - Category B