Lec 22 Heliobacter and GI tract Flashcards
The stomach lining is protected by
a mucus layer
What are ulcers linked to?
Excess acid in the stomach or duodenum
Severe cases of ulcers will causeq
hemorrhages and stomach contents to leak out
__ bacteria is highly associated with ulcrs
heliobacter pylori
Describe h pylori
g neg, spiral, flagella
Humans have different susceptibility to h pylori T/F?
TRUE
What is the job of h pylori; the endproducts are ___
Degrades proteins to make urea; alkaline
__% of people have h pylori in them
50
Risk factors for h pylori colonization are
poor SES, contamination, oral fecal contamination
Is h pylori colonization more likely to occur iun adults or kids?
kids
Early h pylori leads to __ while late leads to __
cancer; ulcers
Extreme high incidence of stomach cancer is in
Japan Chile and Iceland
HWhere are stomach cancer incidence rates higher in the US?
Alaska, Hawaii, New York, DC, Pennsylvania
WHo is stomach cancer most common in?
men over age 40
Helicobacter treatment includes
reducing salt and cured foods, vit C, radiation/chemo
Diagnosing h pylori
culture, antibody for history, detect urease breath test
Medicine to treat h pylori that got recalled is
zantac/ranitidine
We don’t treat heliobacter with antibiotics because
of resistance
What happens to alcoholics with h pylori>
alcoholic gastritis
Helicobacter treatment can regress inflammation of malt, lowering the risk for
lymphoma
Ulcers are linked to stomach cancers/ T/F?
FALSE, no evidence. only evidence that h pylori is related to both things.
Childhood infection can have what affect on adult infection?
limits acid production, but stomach cancer
Adult Childhood infection how many people get ulcers?
1/5
Acid from stomach irritates the esophagus in ___. It is a problem of the ___
GERD; Lower esophageal sphincter
