Lec 22 Heliobacter and GI tract

Question 1

The stomach lining is protected by

Answer 1

a mucus layer

Question 2

What are ulcers linked to?

Answer 2

Excess acid in the stomach or duodenum

Question 3

Severe cases of ulcers will causeq

Answer 3

hemorrhages and stomach contents to leak out

Question 4

__ bacteria is highly associated with ulcrs

Answer 4

heliobacter pylori

Question 5

Describe h pylori

Answer 5

g neg, spiral, flagella

Question 6

Humans have different susceptibility to h pylori T/F?

Answer 6

TRUE

Question 7

What is the job of h pylori; the endproducts are ___

Answer 7

Degrades proteins to make urea; alkaline

Question 8

__% of people have h pylori in them

Answer 8

50

Question 9

Risk factors for h pylori colonization are

Answer 9

poor SES, contamination, oral fecal contamination

Question 10

Is h pylori colonization more likely to occur iun adults or kids?

Answer 10

kids

Question 11

Early h pylori leads to __ while late leads to __

Answer 11

cancer; ulcers

Question 12

Extreme high incidence of stomach cancer is in

Answer 12

Japan Chile and Iceland

Question 13

HWhere are stomach cancer incidence rates higher in the US?

Answer 13

Alaska, Hawaii, New York, DC, Pennsylvania

Question 14

WHo is stomach cancer most common in?

Answer 14

men over age 40

Question 15

Helicobacter treatment includes

Answer 15

reducing salt and cured foods, vit C, radiation/chemo

Question 16

Diagnosing h pylori

Answer 16

culture, antibody for history, detect urease breath test

Question 17

Medicine to treat h pylori that got recalled is

Answer 17

zantac/ranitidine

Question 18

We don’t treat heliobacter with antibiotics because

Answer 18

of resistance

Question 19

What happens to alcoholics with h pylori>

Answer 19

alcoholic gastritis

Question 20

Helicobacter treatment can regress inflammation of malt, lowering the risk for

Answer 20

lymphoma

Question 21

Ulcers are linked to stomach cancers/ T/F?

Answer 21

FALSE, no evidence. only evidence that h pylori is related to both things.

Question 22

Childhood infection can have what affect on adult infection?

Answer 22

limits acid production, but stomach cancer

Question 23

Adult Childhood infection how many people get ulcers?

Answer 23

1/5

Question 24

Acid from stomach irritates the esophagus in ___. It is a problem of the ___

Answer 24

GERD; Lower esophageal sphincter

Question 25

GERD is associated with

Answer 25

hiatal hernia

Question 26

Testing for GERD is done by

Answer 26

an endoscopy

Question 27

How many americans have gerd?

Answer 27

20 million

Question 28

FROm GERD you can advance to ___, and then __.

Answer 28

Barrett’s esophagus which is premalignant; esophageal cancer

Question 29

Where are esophageal cancer rates high?

Answer 29

Asia, Africa

Question 30

In chron’s disease, our immune system is doing what

Answer 30

reading food or something else for an issue (molecular mimicry)

Question 31

Who is at higher risk of Chron’s

Answer 31

smoking Jews

Question 32

Chron’s treatment is

Answer 32

treat symptoms with asprin and corticosteriods, surgery

Question 33

Chron’s treatment is

Answer 33

treat symptoms with aspirin and corticosteriods, surgery

Question 34

Chrons is most common in which areas

Answer 34

US, Canada, AUS, NZ

Question 35

What is the relation of Gastric cancer to CHron’s?

Answer 35

Inverse relationship between incidence in different countries

Question 36

Chron’s disease is possibly waht type of infection due to what bacteria?

Answer 36

zoonotic; m paratuberculosis (possibly correlated)

Question 37

The end result of Chron’s is..

Answer 37

intense inflammation and discomfort