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global health > lecture 2 -coronaviruses > Flashcards

lecture 2 -coronaviruses Flashcards

1
Q

what protein is used to make DNA dependent viruses? this in which stage?

A

DNA DEPENDENT DNA POLYMERASE; DNA replication

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2
Q

WHat are the reverse transcribing viruses?

A

Hepadinaviridae, retroviridae

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3
Q

When RNA-depdendent DNA polymerases make mistakes, they create ____.

A

retroviruses

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4
Q

the flu virus families we are docusing on are

A

orthomyoxyviridae and coronaviridae(coronavirus)

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5
Q

mad cow and toxins are __

A

protien viruses

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6
Q

cell damage, loss of health by a
specific agent

A

disease

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7
Q

Growth or persistence of agent
WITHOUT disease/tissue damage

A

Colonization

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8
Q

Growth of the agent within a host
resulting in damage and disease

A

infection

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9
Q

Time from acquiring the
agent to the time that symptoms are
observed

A

Incubation period -

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10
Q

worldwide epidemic. Black
Death was a (endemic/epidemic/pandemic)

A

Pandemic

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11
Q

An increase in the number of
cases of a disease over that rate
usually found. A rapidly spreading new
disease. Swine Flu

A

epidmic

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12
Q

Commonly distributed in a
region. A common infection.

A

endemic

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13
Q

two or more people, in the same time and
place, with the same symptoms, must be more than
standard number who normally get the disease (food
poisoning versus seasonal flu)

A

outbreak

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14
Q

number of new cases of a disease.in a
given time period

A

incidence

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15
Q

total number of cases old and new.
The total number of ill people in the
population

A

prevalence

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16
Q

loss of life

A

mortality

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17
Q

loss ofhealth andnormal function

A

morbidity

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18
Q

DALY

A

measure of morbid and mortal related to a disease

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19
Q

AIDS is a syndrome T/F?

A

TRUE

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20
Q

A SYNDROME IS always a group of symptoms without a
known cause T/F?

A

FALSE- it couldddd but it also could have several known agents causing it

21
Q

clinical criteria for coronaviruses

A

cough, fever, shortness of breath, and more

22
Q

Diagnostic imaging criteria
for coronaviruses

A

Radiological evidence showing lesions compatible with
COVID-19

23
Q

Three Point Response
to Disease

A

diagnostic test, treat with drug, immunize with vaccine

24
Q

SARS was first diagnosed in a 48 yer old buisinessman travelling from __to__ to__

A

China to HK to Hanoi, Vietnam

25
Q

Case definition of SARS includes

A

resp illness, fever, post 2003, travel or close cotnact in last 10 days

26
Q

SARS IS Closely related to coronaviruses found in:

A

CIVET CATS, HORSESHOE BATS

27
Q

describe SARS genome

A

ss + RNA

28
Q

SARS is transmitted how>

A

air droplets, aerosols, fomites, fluids, endemic to animals

29
Q

the SARS mortality rate is ?

A

9.6%

30
Q

MERS-COV mortality rate is?

A

less than 50% (ABOUT 34%)

31
Q

MERS COV is not human transmissable T/F?

A

TRUE

32
Q

Who is affected most by SARS COV? what type of issues?

A

men; resp and kidney issue

33
Q

the R factor for MERS COV now is? it USED to be?

A

less than 1; 2-4`

34
Q

the reservoir for MERS COV is?

A

egyptian tomb bats, camels

35
Q

the R value for COVID is?

A

2.5

36
Q

MERS virus is grown how (to make vaccines)?

A

Virus grows in pig and bat cells

37
Q

bsesides ppl who else needs to be immunized for MERS?

A

camels

38
Q

describe the genome of COVID? (-/+) (small/large) (__kB) (#proteins)

A

+ ssRNA, large 30kB genome, 20-30proteins

39
Q

How does COVID infect cells

A

enter through nose/mouth, infects airways

40
Q

who in Human Genetics is moresusceptible to COVID?

A

NEANDERTHALS, EAST ASIANS,

41
Q

ADULT COVID SYMPTOMS

A

New loss of taste or smell, amongst others

42
Q

emergency warning signs for COVID-19:
T

A

Trouble breathing, Persistent pain or pressure in the
chest, New confusion, Inability to wake or stay awake,
Bluish lips or face

43
Q

Dermatology symptoms of COVID19

A

COVID toes –
Red or purple toes,
Itchy hives,
Mottled bumps on fingers,
Lacy red rash that spread
across legs and arms

44
Q

COVID Symptoms in Children

A

New loss of taste or smell.
Poor appetite or poor feeding, especially in babies under 1
year old

45
Q

a small amount of children will develop __ from COVID

A

multisystem inflammatory syndrome (MIS-C)

46
Q

can adults get MIS-C?

A

yes

47
Q

intermediate host of COVID zoonosis

A

pangolin

48
Q

what receptor is needed for the COVID lifestyle?

A

Ace2 angiotensin converting enzyme

global health (29 decks)

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