Lecture 17 Immune Disorders

Question 1

The insect stage of ma\larioa vaccines prevent ___

Answer 1

liver infection

Question 2

the liver stage of malaria vacc porevents

Answer 2

blood inf

Question 3

gamete stage of malaria vacc is formed in __ and taken up by__

Answer 3

blood, mosquitos and mating has to happen

Question 4

The issues with TB vaccines are?

Answer 4

latency, strain variation, BCG (current vax) not super effective

Question 5

Self immunity is called

Answer 5

auto immunity

Question 6

Cardinal signs of inflammation are?

Answer 6

redness, swelling, pain, heat

Question 7

Within your body, you can develop autoimmune diseases. how common? to who?

Answer 7

3rd in US, women

Question 8

lack of sleep, buldging eyes (exophthlamos), hyperthyroidism are seen in ?

Answer 8

Grave’s disease

Question 9

What is it called when pathogens have antigens similar to self antigens?

Answer 9

molecular mimicry

Question 10

Strep A has a link to

Answer 10

OCD and PANDAS

Question 11

PANDAS stands for

Answer 11

pediatric autoimmune neuropsychiatric disorders associated with streptochoccal infections

Question 12

Symptoms of PANDAS are

Answer 12

abnormal eating, extreme separtion anxioety, bed wetting, temp[er tantrum, sudden learning issues

Question 13

treatment for PANDAS is

Answer 13

antibiotics

Question 14

Which type of diabetes is associated with children

Answer 14

Type 1

Question 15

How does molecular mimicry occur in type 1 diabetes

Answer 15

the immune system targets pancratic b cells so they cant make insulin

Question 16

Antimicrobial peptides called __ prevent pancreatic inflammation

Answer 16

cathelicidins

Question 17

Myelin sheaths are degreaded in which disease? What does it leave a person with?

Answer 17

MS; scarred tissues

Question 18

Who is more affected by MS?

Answer 18

women 2x than men

Question 19

What type of countries is MS associated with?

Answer 19

High median income countries like the US

Question 20

MS is associated with whihch pathogen?

Answer 20

EBV

Question 21

Lupus is non-fatal, T/F?

Answer 21

FALSE lupus is fatal

Question 22

How tdo we vaccinate and treat lupus?

Answer 22

Vaccinate by E. gallinarum and treat with antibodies

Question 23

If there is a threat to non-self, it is __

Answer 23

inocuous

Question 24

Examples of inucous agents are

Answer 24

allergens

Question 25

Common allergy symptoms. How can allergies kill?

Answer 25

rash, hives; anaphylactic shock

Question 26

Asthma causes

Answer 26

constriction of airways (bronchiocnstriction) and bronchial infection

Question 27

A low level of 4 microbes is a (high/low) risk ofasthma. This is part of the ___

Answer 27

Low; Hygeien hypothesis

Question 28

Helminths are another name for; they are used to

Answer 28

worms; treatments for immune system

Question 29

M paratuberculpsis is associated with

Answer 29

Chrons disease

Question 30

Where is chrons disease present in?

Answer 30

milk,meat,. anf feces of infected cattle

Question 31

Sometimes chron’s has an association to fungi how?

Answer 31

candida causes vaginal yeast infection and malassezia causes dandruff

Question 32

Candida albicans is present in most of us but it can be a normal r strong immune response T/F?

Answer 32

TRUE

Question 33

A strong immune response to Histoplasma can cause

Answer 33

chronic inflammation, calcified mediastinal fibrosis