Lecture 17 Immune Disorders Flashcards

1
Q

The insect stage of ma\larioa vaccines prevent ___

A

liver infection

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2
Q

the liver stage of malaria vacc porevents

A

blood inf

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3
Q

gamete stage of malaria vacc is formed in __ and taken up by__

A

blood, mosquitos and mating has to happen

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4
Q

The issues with TB vaccines are?

A

latency, strain variation, BCG (current vax) not super effective

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5
Q

Self immunity is called

A

auto immunity

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6
Q

Cardinal signs of inflammation are?

A

redness, swelling, pain, heat

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7
Q

Within your body, you can develop autoimmune diseases. how common? to who?

A

3rd in US, women

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8
Q

lack of sleep, buldging eyes (exophthlamos), hyperthyroidism are seen in ?

A

Grave’s disease

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9
Q

What is it called when pathogens have antigens similar to self antigens?

A

molecular mimicry

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10
Q

Strep A has a link to

A

OCD and PANDAS

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11
Q

PANDAS stands for

A

pediatric autoimmune neuropsychiatric disorders associated with streptochoccal infections

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12
Q

Symptoms of PANDAS are

A

abnormal eating, extreme separtion anxioety, bed wetting, temp[er tantrum, sudden learning issues

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13
Q

treatment for PANDAS is

A

antibiotics

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14
Q

Which type of diabetes is associated with children

A

Type 1

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15
Q

How does molecular mimicry occur in type 1 diabetes

A

the immune system targets pancratic b cells so they cant make insulin

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16
Q

Antimicrobial peptides called __ prevent pancreatic inflammation

A

cathelicidins

17
Q

Myelin sheaths are degreaded in which disease? What does it leave a person with?

A

MS; scarred tissues

18
Q

Who is more affected by MS?

A

women 2x than men

19
Q

What type of countries is MS associated with?

A

High median income countries like the US

20
Q

MS is associated with whihch pathogen?

21
Q

Lupus is non-fatal, T/F?

A

FALSE lupus is fatal

22
Q

How tdo we vaccinate and treat lupus?

A

Vaccinate by E. gallinarum and treat with antibodies

23
Q

If there is a threat to non-self, it is __

24
Q

Examples of inucous agents are

25
Common allergy symptoms. How can allergies kill?
rash, hives; anaphylactic shock
26
Asthma causes
constriction of airways (bronchiocnstriction) and bronchial infection
27
A low level of 4 microbes is a (high/low) risk ofasthma. This is part of the ___
Low; Hygeien hypothesis
28
Helminths are another name for; they are used to
worms; treatments for immune system
29
M paratuberculpsis is associated with
Chrons disease
30
Where is chrons disease present in?
milk,meat,. anf feces of infected cattle
31
Sometimes chron's has an association to fungi how?
candida causes vaginal yeast infection and malassezia causes dandruff
32
Candida albicans is present in most of us but it can be a normal r strong immune response T/F?
TRUE
33
A strong immune response to Histoplasma can cause
chronic inflammation, calcified mediastinal fibrosis