Lecture 17 Immune Disorders Flashcards
The insect stage of ma\larioa vaccines prevent ___
liver infection
the liver stage of malaria vacc porevents
blood inf
gamete stage of malaria vacc is formed in __ and taken up by__
blood, mosquitos and mating has to happen
The issues with TB vaccines are?
latency, strain variation, BCG (current vax) not super effective
Self immunity is called
auto immunity
Cardinal signs of inflammation are?
redness, swelling, pain, heat
Within your body, you can develop autoimmune diseases. how common? to who?
3rd in US, women
lack of sleep, buldging eyes (exophthlamos), hyperthyroidism are seen in ?
Grave’s disease
What is it called when pathogens have antigens similar to self antigens?
molecular mimicry
Strep A has a link to
OCD and PANDAS
PANDAS stands for
pediatric autoimmune neuropsychiatric disorders associated with streptochoccal infections
Symptoms of PANDAS are
abnormal eating, extreme separtion anxioety, bed wetting, temp[er tantrum, sudden learning issues
treatment for PANDAS is
antibiotics
Which type of diabetes is associated with children
Type 1
How does molecular mimicry occur in type 1 diabetes
the immune system targets pancratic b cells so they cant make insulin
Antimicrobial peptides called __ prevent pancreatic inflammation
cathelicidins
Myelin sheaths are degreaded in which disease? What does it leave a person with?
MS; scarred tissues
Who is more affected by MS?
women 2x than men
What type of countries is MS associated with?
High median income countries like the US
MS is associated with whihch pathogen?
EBV
Lupus is non-fatal, T/F?
FALSE lupus is fatal
How tdo we vaccinate and treat lupus?
Vaccinate by E. gallinarum and treat with antibodies
If there is a threat to non-self, it is __
inocuous
Examples of inucous agents are
allergens
Common allergy symptoms. How can allergies kill?
rash, hives; anaphylactic shock
Asthma causes
constriction of airways (bronchiocnstriction) and bronchial infection
A low level of 4 microbes is a (high/low) risk ofasthma. This is part of the ___
Low; Hygeien hypothesis
Helminths are another name for; they are used to
worms; treatments for immune system
M paratuberculpsis is associated with
Chrons disease
Where is chrons disease present in?
milk,meat,. anf feces of infected cattle
Sometimes chron’s has an association to fungi how?
candida causes vaginal yeast infection and malassezia causes dandruff
Candida albicans is present in most of us but it can be a normal r strong immune response T/F?
TRUE
A strong immune response to Histoplasma can cause
chronic inflammation, calcified mediastinal fibrosis
