Lec 24 Hepatitis Viruses Flashcards

1
Q

What is hepatitis?

A

WHen the liver is inflamed

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2
Q

What is hepatitis caused by?

A

infectious/toxic agents, can be inherited or autoimmune

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3
Q

What are acute specific symptoms for hepatitis?

A

jaundice, megaly, bruising, confusion, bleeding, etc.

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4
Q

Who is the hep A vaccine rec’d for?

A

travelling to endemic areas, MSM, homeless, incarcerated, drug users

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5
Q

The product of RBC breakdown is

A

bilirubin

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6
Q

Fecal oral transmitted Hepatitis types

A

A and E

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7
Q

Inflammation for how long is considered chronic?

A

more than 6mo

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8
Q

Chronic hep symptoms are

A

cirrhosis (fibrosis)

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9
Q

What are the major outbreak type of hepatitis viruses

A

fecal orally transmitted

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10
Q

Hep A immunity is?

A

long term immunity

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11
Q

Hep A treatment is?

A

not available

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12
Q

The US does not have hep outbreaks T?F?

A

FALSE- it does happen!! esp in incarcerated/homeless/drug use

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13
Q

There is no chronic form of hep E T/F?

A

TRUE, only acute

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14
Q

Who is at risk for death for hep E?

A

Pregnant women

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15
Q

Hep A and E can be administered together T/F?

A

FALSE there is no Hep E vaccine yet!

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16
Q

What are the bloodborne hepatitis types? Which of these 3 is the only RNA virus?

A

B C and D; B is the only RNA virus

17
Q

Hep B is treated with

A

antiviral drugs a pill a day

18
Q

What is hep B a primary cause of?

A

Cirrhosis and then Liver cancer

19
Q

How is hep B transmitted?

A

Injection, healthcare setting, mom to baby, sex

20
Q

What is the outcome of a newborn affected with hep B?

A

Chronic carriers

21
Q

What is the outcome of an adult affected with hep B?

A

acute symptoms

22
Q

You can take a post exposure vaccine if exposed to hep B via needle,T/F?

A

TRUE wthin 24 hours

23
Q

Describe hep D’s living needs

A

can only live with hep B (co infection or superinfection with an existing hep B)

24
Q

HBV/HDV combo can accelerate cirrhosis progression by how much?

A

a decade compared to monoinfection

25
The cancer causing hepatitis viruses are
Hep C and B
26
Which hepatitis integrates into our genome?
27
What is the treatment for hep C?
antivirals but no vaccine
28
What is the issue with detecting hep C?
most don't have any symptoms at all
29
Hep C, like B can cause
cirrhosis and then liver cancer
30
The most common reason for liver transplants is
hep C
31
We started HIV and Hep C testing since
the 90's
32
The high risk group for hep c is
hemophiliacs, Injection drug users, HIV
33
Describe the treatment and prevention of hep C
ridiculously expensive pill ($1000/day), and no vaccine