Lec 24 Hepatitis Viruses Flashcards

1
Q

What is hepatitis?

A

WHen the liver is inflamed

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2
Q

What is hepatitis caused by?

A

infectious/toxic agents, can be inherited or autoimmune

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3
Q

What are acute specific symptoms for hepatitis?

A

jaundice, megaly, bruising, confusion, bleeding, etc.

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4
Q

Who is the hep A vaccine rec’d for?

A

travelling to endemic areas, MSM, homeless, incarcerated, drug users

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5
Q

The product of RBC breakdown is

A

bilirubin

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6
Q

Fecal oral transmitted Hepatitis types

A

A and E

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7
Q

Inflammation for how long is considered chronic?

A

more than 6mo

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8
Q

Chronic hep symptoms are

A

cirrhosis (fibrosis)

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9
Q

What are the major outbreak type of hepatitis viruses

A

fecal orally transmitted

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10
Q

Hep A immunity is?

A

long term immunity

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11
Q

Hep A treatment is?

A

not available

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12
Q

The US does not have hep outbreaks T?F?

A

FALSE- it does happen!! esp in incarcerated/homeless/drug use

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13
Q

There is no chronic form of hep E T/F?

A

TRUE, only acute

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14
Q

Who is at risk for death for hep E?

A

Pregnant women

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15
Q

Hep A and E can be administered together T/F?

A

FALSE there is no Hep E vaccine yet!

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16
Q

What are the bloodborne hepatitis types? Which of these 3 is the only RNA virus?

A

B C and D; B is the only RNA virus

17
Q

Hep B is treated with

A

antiviral drugs a pill a day

18
Q

What is hep B a primary cause of?

A

Cirrhosis and then Liver cancer

19
Q

How is hep B transmitted?

A

Injection, healthcare setting, mom to baby, sex

20
Q

What is the outcome of a newborn affected with hep B?

A

Chronic carriers

21
Q

What is the outcome of an adult affected with hep B?

A

acute symptoms

22
Q

You can take a post exposure vaccine if exposed to hep B via needle,T/F?

A

TRUE wthin 24 hours

23
Q

Describe hep D’s living needs

A

can only live with hep B (co infection or superinfection with an existing hep B)

24
Q

HBV/HDV combo can accelerate cirrhosis progression by how much?

A

a decade compared to monoinfection

25
Q

The cancer causing hepatitis viruses are

A

Hep C and B

26
Q

Which hepatitis integrates into our genome?

A
27
Q

What is the treatment for hep C?

A

antivirals but no vaccine

28
Q

What is the issue with detecting hep C?

A

most don’t have any symptoms at all

29
Q

Hep C, like B can cause

A

cirrhosis and then liver cancer

30
Q

The most common reason for liver transplants is

A

hep C

31
Q

We started HIV and Hep C testing since

A

the 90’s

32
Q

The high risk group for hep c is

A

hemophiliacs, Injection drug users, HIV

33
Q

Describe the treatment and prevention of hep C

A

ridiculously expensive pill ($1000/day), and no vaccine