Lec 24 Hepatitis Viruses Flashcards
What is hepatitis?
WHen the liver is inflamed
What is hepatitis caused by?
infectious/toxic agents, can be inherited or autoimmune
What are acute specific symptoms for hepatitis?
jaundice, megaly, bruising, confusion, bleeding, etc.
Who is the hep A vaccine rec’d for?
travelling to endemic areas, MSM, homeless, incarcerated, drug users
The product of RBC breakdown is
bilirubin
Fecal oral transmitted Hepatitis types
A and E
Inflammation for how long is considered chronic?
more than 6mo
Chronic hep symptoms are
cirrhosis (fibrosis)
What are the major outbreak type of hepatitis viruses
fecal orally transmitted
Hep A immunity is?
long term immunity
Hep A treatment is?
not available
The US does not have hep outbreaks T?F?
FALSE- it does happen!! esp in incarcerated/homeless/drug use
There is no chronic form of hep E T/F?
TRUE, only acute
Who is at risk for death for hep E?
Pregnant women
Hep A and E can be administered together T/F?
FALSE there is no Hep E vaccine yet!
What are the bloodborne hepatitis types? Which of these 3 is the only RNA virus?
B C and D; B is the only RNA virus
Hep B is treated with
antiviral drugs a pill a day
What is hep B a primary cause of?
Cirrhosis and then Liver cancer
How is hep B transmitted?
Injection, healthcare setting, mom to baby, sex
What is the outcome of a newborn affected with hep B?
Chronic carriers
What is the outcome of an adult affected with hep B?
acute symptoms
You can take a post exposure vaccine if exposed to hep B via needle,T/F?
TRUE wthin 24 hours
Describe hep D’s living needs
can only live with hep B (co infection or superinfection with an existing hep B)
HBV/HDV combo can accelerate cirrhosis progression by how much?
a decade compared to monoinfection
The cancer causing hepatitis viruses are
Hep C and B
Which hepatitis integrates into our genome?
What is the treatment for hep C?
antivirals but no vaccine
What is the issue with detecting hep C?
most don’t have any symptoms at all
Hep C, like B can cause
cirrhosis and then liver cancer
The most common reason for liver transplants is
hep C
We started HIV and Hep C testing since
the 90’s
The high risk group for hep c is
hemophiliacs, Injection drug users, HIV
Describe the treatment and prevention of hep C
ridiculously expensive pill ($1000/day), and no vaccine