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global health > lecture 9 ebola AFM Norovirus > Flashcards

lecture 9 ebola AFM Norovirus Flashcards

1
Q

Marburg was identified in who?

A

green monkeys

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2
Q

how ismarburg spread? one concern was __

A

through body fluids; air travel

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3
Q

marburg treatment includes

A

supportive care but no drugs

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4
Q

what vax might work for marburg?

A

ebola vaccine

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5
Q

ebola is found in which locations?

A

sudan, congo, uganda, zaire

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6
Q

ebola tends to be in which reservoir?

A

bats, chimpanzees

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7
Q

how is ebola spread?

A

from bats to monkeys/antelopes to humans, or from bats to humans

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8
Q

marburg and ebola were found in which type of bat?

A

fruit bat

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9
Q

ebola marburg and lassa are what type of disease?

A

hemmorhhagic fever

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10
Q

locations where marburg happened

A

uganda, kenya

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11
Q

lassa happened where?

A

nigeria

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12
Q

lassa is a member of which virus family?

A

arenaviruses

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13
Q

why was the ebola outbreak in west africa different?

A

it was in cities nad not rural areas

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14
Q

how is lassa fever spread? and carried?

A

carried by rats in urine/feces, spread from human to human direct contact

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15
Q

avg percent mortality from lassa

A

1%

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16
Q

lassa incubation time

A

1-3 wk

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17
Q

drug to treat lassa

A

ribavirin but early on

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18
Q

symotoms of lassaf ever

A

fever, aches and pains
multi-organ failure
lungs, heart, GI tract, nerves

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19
Q

one effect of ebola onwest africa

A

destroyed the economy

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20
Q

mistakes made in sierra leone during ebola crisis

A

poor water sanitations, no body bags, inexperienced health care workers, weak leaders,power supply and funding low

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21
Q

what are Spread in health-care facilities where sterile materials
are at a premium. This is a major problem.

A

hemorrhagic viruses

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22
Q

marburg mort rate

A

25-90%

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23
Q

what was the source of the marburg virus and where?

A

Marburg Germany,from
green monkeys imported from Africa

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24
Q

where in the body do marburg symptoms show up?>

A

multiorgan issues

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25
Q

norovirus is mostly associated with hwhich place?

A

cruise ships

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26
Q

norovirus is ds/ss and DNA/RNA?

A

ss RNA

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27
Q

norovirus is very infectious T?F?

A

TRUE

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28
Q

symptoms of noroviorus

A

diarhhea, vomitting

29
Q

how does norovirus spread?

A

fecal, oral, fomite, aerosol

30
Q

how does norovirus spread?

A

person to enviroenment to person

31
Q

how long does norovirus imunite last?

A

1 year, no permamanent

32
Q

norovirus’s cycle lasts how long? which months?

A

1 year; Nov to May

33
Q

what symptoms does ebola cause

A

general malaise, organ fail, death

34
Q

mortality for ebola is low T/F?

A

FALSE

35
Q

new version of ebola (2012) called

A

bundibugyo ebolavirus

36
Q

bundibugyo ebola symptopms

A

fever, vomit, diarrhea, system fail

37
Q

who got sick from ebola?

A

relatives, cotnacts, health care workers,

38
Q

how did pekple outside of african coutnries contact ebola

A

travelling to africa and back home

39
Q

post ebola virus syndrome

A

blind, eye issues, chronic pain, meningitis

40
Q

in congo, ebola had a high coinfection with what

A

malaria

41
Q

how people fought hte fear outbreak aspect of ebola

A

CUBE transparent tents and transparent body bags for peace of mind

42
Q

the 12th wave of ebola affected who?

A

farmers and their wives

43
Q

the distant cousin virys tio ebola is

A

lujo virus

44
Q

what is lujo’s reservoir

A

rodents

45
Q

tanzania had a similar ebola related symptom, what was it?

A

bleeding in the mouth

46
Q

crimean congo hemorrhagic fever affected who?

A

epople who had direct contact w livestock

47
Q

_%mort for crimean congo

A

30%

48
Q

what was the vector for crimean congo fever?

A

ticks

49
Q

define acute flaccid myelitis

A

sudden onset limp inflammation of spinal cord

50
Q

who does AFM affect

A

kids

51
Q

symptoms of AFM

A

weak muscle andreflexes, lost muscle tone, slurred speech,hard to wallow, facial droop

52
Q

symptoms of AFM

A

weak muscle andreflexes, lost muscle tone, slurred speech,hard to wallow, facial droopse

53
Q

severeAFM symptoms

A

the normal ones and then severe resp failure

54
Q

diagnosing AFM is as easy as…!

A

MRI for lesions to spinal cord, high WBC, PCR for virus

55
Q

AFM coud be caused by ?

A

enteroviruses, fever, mild respiratoru illness

56
Q

AFM can cause this dieases which shows up in the body wehere?

A

polio in hand foot and mouth

57
Q

the __ clade which causes AFM recocurs how often in the US?

A

d48; ever 2 years

58
Q

what are similar syndroms to AFM?

A

polio, guillan barre, transverse myelitis

59
Q

what are some similar toxins to AFM?

A

diptheria, botulinism, porphyria

60
Q

how long after contracting norovirus fdoes disease happen?

A

within 24hr

61
Q

what is an AFM treatment?

A

nerve transfers (they did em at St. Luke’e Hospital!)

62
Q

severe cases of AFM are treated HOW?

A

MECHANIACAL VENTS

63
Q

ways to treat AFM symptoms if not severe

A

phys/occupational therapy

64
Q

how is bolivian hemmorhagic fever spread?

A

by mice

65
Q

what virus causes bolivian hemmorhagic fever?

A

machupo virus

66
Q

bolivian hemm fever is also called?

A

black typhus

67
Q

how is bolivian hemm fever spread?

A

by mice (rarely human to human)

68
Q

which is faster, D68 or polio?

A

polio

69
Q

which is less virulent, D68 or polio?

A

D68

global health (29 decks)

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