lecture 9 ebola AFM Norovirus Flashcards by M Batool

Marburg was identified in who?

green monkeys

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how ismarburg spread? one concern was __

through body fluids; air travel

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marburg treatment includes

supportive care but no drugs

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what vax might work for marburg?

ebola vaccine

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ebola is found in which locations?

sudan, congo, uganda, zaire

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ebola tends to be in which reservoir?

bats, chimpanzees

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how is ebola spread?

from bats to monkeys/antelopes to humans, or from bats to humans

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marburg and ebola were found in which type of bat?

fruit bat

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ebola marburg and lassa are what type of disease?

hemmorhhagic fever

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locations where marburg happened

uganda, kenya

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lassa happened where?

nigeria

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lassa is a member of which virus family?

arenaviruses

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why was the ebola outbreak in west africa different?

it was in cities nad not rural areas

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how is lassa fever spread? and carried?

carried by rats in urine/feces, spread from human to human direct contact

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avg percent mortality from lassa

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lassa incubation time

1-3 wk

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drug to treat lassa

ribavirin but early on

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symotoms of lassaf ever

fever, aches and pains
multi-organ failure
lungs, heart, GI tract, nerves

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one effect of ebola onwest africa

destroyed the economy

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mistakes made in sierra leone during ebola crisis

poor water sanitations, no body bags, inexperienced health care workers, weak leaders,power supply and funding low

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what are Spread in health-care facilities where sterile materials
are at a premium. This is a major problem.

hemorrhagic viruses

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marburg mort rate

25-90%

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what was the source of the marburg virus and where?

Marburg Germany,from
green monkeys imported from Africa

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where in the body do marburg symptoms show up?>

multiorgan issues

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norovirus is mostly associated with hwhich place?

cruise ships

norovirus is ds/ss and DNA/RNA?

ss RNA

norovirus is very infectious T?F?

TRUE

symptoms of noroviorus

diarhhea, vomitting

how does norovirus spread?

fecal, oral, fomite, aerosol

how does norovirus spread?

person to enviroenment to person

how long does norovirus imunite last?

1 year, no permamanent

norovirus's cycle lasts how long? which months?

1 year; Nov to May

what symptoms does ebola cause

general malaise, organ fail, death

mortality for ebola is low T/F?

FALSE

new version of ebola (2012) called

bundibugyo ebolavirus

bundibugyo ebola symptopms

fever, vomit, diarrhea, system fail

who got sick from ebola?

relatives, cotnacts, health care workers,

how did pekple outside of african coutnries contact ebola

travelling to africa and back home

post ebola virus syndrome

blind, eye issues, chronic pain, meningitis

in congo, ebola had a high coinfection with what

malaria

how people fought hte fear outbreak aspect of ebola

CUBE transparent tents and transparent body bags for peace of mind

the 12th wave of ebola affected who?

farmers and their wives

the distant cousin virys tio ebola is

lujo virus

what is lujo's reservoir

rodents

tanzania had a similar ebola related symptom, what was it?

bleeding in the mouth

crimean congo hemorrhagic fever affected who?

epople who had direct contact w livestock

_%mort for crimean congo

30%

what was the vector for crimean congo fever?

ticks

define acute flaccid myelitis

sudden onset limp inflammation of spinal cord

who does AFM affect

kids

symptoms of AFM

weak muscle andreflexes, lost muscle tone, slurred speech,hard to wallow, facial droop

symptoms of AFM

weak muscle andreflexes, lost muscle tone, slurred speech,hard to wallow, facial droopse

severeAFM symptoms

the normal ones and then severe resp failure

diagnosing AFM is as easy as...!

MRI for lesions to spinal cord, high WBC, PCR for virus

AFM coud be caused by ?

enteroviruses, fever, mild respiratoru illness

AFM can cause this dieases which shows up in the body wehere?

polio in hand foot and mouth

the __ clade which causes AFM recocurs how often in the US?

d48; ever 2 years

what are similar syndroms to AFM?

polio, guillan barre, transverse myelitis

what are some similar toxins to AFM?

diptheria, botulinism, porphyria

how long after contracting norovirus fdoes disease happen?

within 24hr

what is an AFM treatment?

nerve transfers (they did em at St. Luke'e Hospital!)

severe cases of AFM are treated HOW?

MECHANIACAL VENTS

ways to treat AFM symptoms if not severe

phys/occupational therapy

how is bolivian hemmorhagic fever spread?

by mice

what virus causes bolivian hemmorhagic fever?

machupo virus

bolivian hemm fever is also called?

black typhus

how is bolivian hemm fever spread?

by mice (rarely human to human)

which is faster, D68 or polio?

polio

which is less virulent, D68 or polio?

D68