lecture 6 flu Flashcards
vaccine sideeffects
soreness, fatigue, muscle ache, fever, chill, joint pain, headache
tight throat, swole lips, hives, stomach pain are signs of?
anaphylaxis
in berkeley, CA, a vaccine was contaminated for which virus?
live polio virus
the cutter incident caused which symptoms in which pop?
permanent paralyzed, death; kids
green monkey cell vaccines were contaminated with __? poss sympt?
SV40; cancer
swine flu vaccine linked to what syndrome? what does this synfrome do?
guillian barre syndrome; CNS paralysis
lessons learned from covid,
scale up testing, trust data, diverse voices, vaccine, improve communication
influenza means?
“influence of cold”
what type of bacteria/virus is influenza
RNA transcription virus
key surface proteins for influenza are?
henmagglutinin and neuraminidase
type A of influenza transmission
humans and animals
type B of influenza transmission
only people
type C of influenza transmission
only people (Mild)
types of Type A influenza
H AND N
cutter incident spurred what? what disease was it or?
regulations to make vaccines safer; polio
RNA viruses have antigentic shift T/F?
FALSE they have antigenetic DRIFT
we need a new fluvaccine each year because opf
new variants of flu yearly due to antigentic drift
atigentic shifts can cause__
pandemics
how many pieces of RNA does flu virus have? how do they assort themselves?
8; independently
flu antigentic shift happens due to reassortment with whic strain?
avian strains; their H and N adapt to human ones
reassortment of flu can happen in humans and which animals?
other mammals like horses a nd pigs
flu cyclic causes how many deaths in a year typically? inthe UNited states
15,000-20,000 deaths yearly in the USA
colds are a syndrome T/F?
TRUE
extreme exhaustion,. cold or flu?
flu
fever,. cold or flu
mostly flu
prominent headache ,. cold or flu
flu
stuffy nose. . cold or flu?
cold
sore throat . cold or flu
cold
chest discomfor and cough . cold or flu?
either
general aches and pains . cold or flu? how long does it last?
mostly flu lasting 2-3 wk
who has flu longer, kids or adults?
kids
influenza complications?
severe respiratory disease, pneumonia, s.aureus
lung colonization with ____ before flu can be protection?
s. pneumoniae
key to influenza transmission is?
kids!
how many % cases of influenza are asymptomatic?
33%
cyclic nature of flu in US is in which months?
october-feb
flu was reduced in which year due to prevention efforts?
2020 bc of COVID prevention efforts overlapped w flu prevention efforts
after 2020, when did flu cases rise?
2022-23
new flu drugs need to be taken when?
within 48 hours AFTER flu symptoms start
neuraminidase inhibitor drugs are
relenza and tamiflu
old way to grow flu vaccines was grown in?
chicken eggs
new vaccines are grown where? what is it called
insect cells; flublok
which viral proteins are grown in flublok?
HA viral proteins. no virus
which influnexa type is stable?
type B
type A H1N1 is also what?
a swine flu virus
everytime you get a flu vax, you are vaxxed against which viruses?
how effective is flu vax?
40-60%
how long it takes for flu vaccine to be effeciti=ve?
2 weeks
dont get a flu vaccine if”
egg allergy, previous reaction, history of guillan barre
the spanish flu is from spain T?F?
FALSE it is from germany
the spanish flu happened when?
during WWII trench warfare
spanish influenza spread how?
patriotic parades, ships and male barracks, troops, reduced healthcare bc doctors overseas
spanish influenza suymptoms were
blue face (cyanosis), high fever, severe penumonia, death
spanish flu killed who?
veruy old and very young
