Lec 25 Intestinal Diseases Flashcards

1
Q

Colon contains how many microbes? How many cells are in our body?

A

10^14 microbes, 10^13 cells in body

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2
Q

Normal flora of GI tract do what jobs?

A

digestion, vitamin secretion, work immune system, prevent pathogens from growing

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3
Q

What is something that can disrupt normal flora?

A

antibiotics

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4
Q

House dust has the same microbes as

A

baby feces

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5
Q

Transmission of diarrhea is

A

fecal/oral or environmental/oral

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6
Q

Who is most affected with diarrhea?

A

children

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7
Q

Ecoli is a model organism that is a marker for what?

A

Coliform

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8
Q

Enterotoxigenic e coli ETEC is what?

A

traveler’s diarrhea

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9
Q

Enteroinvasive e coli EIEC is what?

A

bloody diarrhea that goes through intestine ET

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10
Q

Enteropathogenic E coli is what? EPEC

A

hospital baby diarrhea that has no toxin or invasion

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11
Q

Enterohemorrhagic E coli EHEC causes what?

A

Hemolytic uremic syndrome and kidney failure

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12
Q

EHEC is what strain? Where is it mostly present?

A

O157: H7; cattle (raw meat)

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13
Q

Classify vibrio cholera

A

g neg, toxin producing

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14
Q

Where is v cholera found?

A

brackish water (saltwater moving into freshwater or vice versa)

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15
Q

Cholera causes what symptoms?

A

severe dehydration because of lots of diarrhea. shock and throw up too

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16
Q

Which blood type is most susceptible to v cholera?

A

blood type O

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17
Q

Which blood type is least susceptible to v cholera?

A

blood type AB

18
Q

Treatment of cholera includes?

A

IV, rehydration, support

19
Q

Does a cholera vaccine exist?

A

Yes

20
Q

Salmonella is __ so it is associated with___

A

zoonosis, turtles,chickens,eggs

21
Q

Mortality for salmonella is __%

A

10

22
Q

Does a salmonella vaccine exist?

A

Yes

23
Q

Describe shigella?

A

g neg, produce toxin,

24
Q

The g neg diseases intestinal are?

A

cholera, shigella, salmonella, campylobacter, c diff

25
Q

Campylobacter is associated with

A

raw chicken, tap water etc

26
Q

Describe c diff bacteria

A

anaerobic, makes spores, makes a toxin

27
Q

C diff can cause what?

A

pseudomembranous colitis

28
Q

Describe l monocytogenes, who is most susceptible?

A

g POS, pregnant women/elderly

29
Q

Listeria is able to grow in which unexpected place?

A

the fridge

30
Q

How do we treat bacterial intestinal infections?

A

fluid, sulfa drugs, anti-diarrheals

31
Q

What are the viral intestinal diseases?

A

rotavirus, norovirus

32
Q

Describe rotavirus makeup:

A

dsRNA

33
Q

Where is rotovirus most common

A

south africa, asia, south india, south america

34
Q

How can we diagnose rotavirus?

A

as an outbreak, viral antigens in ELISA

35
Q

What are viruses that don’t make diarrhea but attack intestine?

A

Adeno and entero viruses, hep A and E

36
Q

Individual prevention of intestinal diseases can be done by

A

handwashing, cooking meat, using CDC/FDA rules

37
Q

You can get e coli 0157 H7, salmonella, and helminths from?

A

Beef

38
Q

You can get l monocytogenes from?

A

Deli meats

39
Q

You can get salmonella, campylobacter, helminths from?

A

Poultry

40
Q

You can get v cholerae, typhoid, giardia, entameoba, helminths, cyrptosporidium

A

water

41
Q

You can get salmonella , shigela, helminths, listeria, e coli 0157 H7 from?

A

Vegetables