Lec 25 Intestinal Diseases Flashcards

1
Q

Colon contains how many microbes? How many cells are in our body?

A

10^14 microbes, 10^13 cells in body

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2
Q

Normal flora of GI tract do what jobs?

A

digestion, vitamin secretion, work immune system, prevent pathogens from growing

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3
Q

What is something that can disrupt normal flora?

A

antibiotics

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4
Q

House dust has the same microbes as

A

baby feces

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5
Q

Transmission of diarrhea is

A

fecal/oral or environmental/oral

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6
Q

Who is most affected with diarrhea?

A

children

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7
Q

Ecoli is a model organism that is a marker for what?

A

Coliform

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8
Q

Enterotoxigenic e coli ETEC is what?

A

traveler’s diarrhea

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9
Q

Enteroinvasive e coli EIEC is what?

A

bloody diarrhea that goes through intestine ET

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10
Q

Enteropathogenic E coli is what? EPEC

A

hospital baby diarrhea that has no toxin or invasion

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11
Q

Enterohemorrhagic E coli EHEC causes what?

A

Hemolytic uremic syndrome and kidney failure

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12
Q

EHEC is what strain? Where is it mostly present?

A

O157: H7; cattle (raw meat)

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13
Q

Classify vibrio cholera

A

g neg, toxin producing

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14
Q

Where is v cholera found?

A

brackish water (saltwater moving into freshwater or vice versa)

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15
Q

Cholera causes what symptoms?

A

severe dehydration because of lots of diarrhea. shock and throw up too

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16
Q

Which blood type is most susceptible to v cholera?

A

blood type O

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17
Q

Which blood type is least susceptible to v cholera?

A

blood type AB

18
Q

Treatment of cholera includes?

A

IV, rehydration, support

19
Q

Does a cholera vaccine exist?

20
Q

Salmonella is __ so it is associated with___

A

zoonosis, turtles,chickens,eggs

21
Q

Mortality for salmonella is __%

22
Q

Does a salmonella vaccine exist?

23
Q

Describe shigella?

A

g neg, produce toxin,

24
Q

The g neg diseases intestinal are?

A

cholera, shigella, salmonella, campylobacter, c diff

25
Campylobacter is associated with
raw chicken, tap water etc
26
Describe c diff bacteria
anaerobic, makes spores, makes a toxin
27
C diff can cause what?
pseudomembranous colitis
28
Describe l monocytogenes, who is most susceptible?
g POS, pregnant women/elderly
29
Listeria is able to grow in which unexpected place?
the fridge
30
How do we treat bacterial intestinal infections?
fluid, sulfa drugs, anti-diarrheals
31
What are the viral intestinal diseases?
rotavirus, norovirus
32
Describe rotavirus makeup:
dsRNA
33
Where is rotovirus most common
south africa, asia, south india, south america
34
How can we diagnose rotavirus?
as an outbreak, viral antigens in ELISA
35
What are viruses that don't make diarrhea but attack intestine?
Adeno and entero viruses, hep A and E
36
Individual prevention of intestinal diseases can be done by
handwashing, cooking meat, using CDC/FDA rules
37
You can get e coli 0157 H7, salmonella, and helminths from?
Beef
38
You can get l monocytogenes from?
Deli meats
39
You can get salmonella, campylobacter, helminths from?
Poultry
40
You can get v cholerae, typhoid, giardia, entameoba, helminths, cyrptosporidium
water
41
You can get salmonella , shigela, helminths, listeria, e coli 0157 H7 from?
Vegetables