lec 16- vaccines Flashcards

1
Q

Two types of immunity are

A

innnate and adaptive

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2
Q

An antigen is a component of ___

A

A pathogen

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3
Q

Adaptive immune responses recognizes

A

Self and non-self

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4
Q

What types of cells are used int eh adaptive immune response?

A

T cells and B cells

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5
Q

B cells differentiate into __. 10% differntate into.

A

plasma cells; memory cells

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6
Q

What do plasma cells secrete?

A

Plasma cells secrete antibodies.

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7
Q

What do B cells make?

A

B cells make antibodies to antigens.

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8
Q

What type of T cell is a killer?

A

CD8 Cytotoxic T cells kill cells that are infected with pathogens.

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9
Q

A small % of CD8 T cells can remain as?

A

Memory cells

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10
Q

Which cells don’t kill but they help manage the immune resposne?

A

CD4 helper T cells.

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11
Q

Which types of vaccines usually need booster shots?

A

Subunit and toxoid vaccines.

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12
Q

Lifelong immunity is achieved by which type of vaccine?

A

Attenuated vaccines

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13
Q

Vaccines deliberately induce an immune adaptive response by:

A

INjection of a dead or non pathogenic form of a pathogen.

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14
Q

Name some newer approaches to the types of vaccines.

A

Peptide-based, mRNA, recombinant, DNA

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15
Q

The R value for COVID is?

A

12-15

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16
Q

The only human disease that has been eliminated from the planet is?

A

Smallpox

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17
Q

How did the 老中国人 prevent smallpox?

A

Variolation- dried smallpox dust was inhaled

18
Q

Edward Kardashian-Jenner made what?

A

A smallpox vaccine

19
Q

Human vaccine requirements/eligiblity:

A

Humans are the only host, prodivdes long lasting immunity and it is immediate

20
Q

What are two vaccines used for polio?

A

Salk (injected) and Sabin (oral)

21
Q

The diptheria vaccine is called?

22
Q

DTP/DTwP is against which dseases?

A

Diptheria toxoid, tetanus toxoid, pertussis

23
Q

How often should you get tetanus boosters?

A

every 10 years or more if in disaster areas

24
Q

There is a misconception about the link btw vaccines and ___

A

ASD- autism spectrum disorder

25
What are need-less vaccines made of ?
Sugar
26
The mRNA vaccine is troublesome to deliverbecause of?
Because of the low temp needed for storatge
27
The ideal vaccine is:
protective, polyvalent, safe
28
Which type of polio is still around, and how many types are there?
Type 1 is here, 2 and 3 were eliminated.
29
Describe cornebacterium diptheriae
g pos with cell wall bacteria
30
Diptheria causes a risk for?
suffocation
31
Cloistridium tetani causes what disease?
tetanus aka lockjaw
32
dsceribe the tetanus bacteria
g pos with cell wall
33
The way tetanus travels is...
a super exotoxin that moves from an impalement to spinal cord
34
Describe hemophilia type B
g neg with membrane
35
How does haemophilus influznea B invade body? Who mostly affected
goes into resp tract then blood; kids
36
Varicella causes _# of infections called and who get it?
2; frst - chickenpox in kids ; second- shingles in adults
37
What type of virus is chickenpox?
Herpesvisu.
38
What vaccine type is used for measles?
LIve attenuated viral vaccine
39
The most contagious dsaese is __. Who is the host.
measles; only humans
40
What toxin causes measles?
the rubella (mild) rna virus and rubeolla (severe) rna virus
41
Describe the bacteria causing pertsses
g neg with outer membrane
42
Out of control diseases
TB, HIV, malaria, HepC, and more