Vulvar Cancer Flashcards
What is the main type of vulvar cancer?
Squamous cell carcinoma
Who is most affected by vulvar cancer?
Women aged 65
Is vulvar cancer common?
No- It is very rare
What is vulvar intraepithelial neoplasia (VIN)?
Abnormal proliferation of squamous epithelium
Can progress to carcinoma
What is vulvar epithelial neoplasia associated with?
HPV
Which lymph nodes does vulvar cancer normally spread to?
Inguinal
Femoral
Pelvic
What are the main risk factors for vulval carcinoma?
- Age
- Human papilloma virus (HPV) infection
- Vulval intraepithelial neoplasia (VIN)
- Immunosuppression
- Lichen sclerosus
What are the main risk factors for vulval carcinoma?
- Age
- Human papilloma virus (HPV) infection
- Vulval intraepithelial neoplasia (VIN)
- Immunosuppression
- Lichen sclerosus
What are the main clinical presentations of vulval carcinoma?
- Lump on the labia majora
- Inguinal lymphadenopathy
- Itching
- Non-healing ulcer on the labia majora
- Vulval pain
What 2 clinical signs present on the labia majora?
Non-healing ulcer
Lump
How is vulval carcinoma diagnosed?
Examination- Lump or ulceration is suspicious
How is the diagnosis of vulval carcinoma confirmed?
By a punch biopsy or excisional biopsy
What is HPV associated vulval carcinoma associated with?
Past history of intra-epithelial neoplasia
What is non-HPV related vulval carcinoma associated with?
Lichen sclerosus
skin condition which causes itchy white patches on genitals
What is the management of primary vulvar cancer?
Radical resection of the primary tumour
