Intrahepatic Cholestasis of Pregnancy Flashcards
What is intrahepatic cholestasis of pregnancy also referred to as?
Obstetric cholestasis
What is intrahepatic cholestasis of pregnancy associated with?
Increased risk of stillbirth
What are the main presenting features of intrahepatic cholestasis of pregnancy?
Intense pruritis
Detectable jaundice
Raised bilirubin
Where on the body is the pruritis worse in someone with intrahepatic cholestasis?
Palms, Soles and abdomen
What is the main management to avoid the risk of stillbirth in someone with intrahepatic cholestasis?
Induction of labour at 37-38 weeks
What can be given to help with the pruritis in someone with intrahepatic cholestasis?
Ursodeoxycholic acid
What is there the risk of in someone with intrahepatic cholestasis?
Recurrence in subsequent pregnancies
Whatis obstetric cholestasis a common cause of?
Itch in the third trimester of pregnancy
How will the LFT’s be affected in someone with intrahepatic cholestasis of pregnancy?
High ALP and GGT
Lesser rise in ALT
Raised bilirubin
What other clinical features might someone with intrahepatic cholestasis of prenancy present with?
Jaundice
Right upper quadrant pain
Steatorrhoea
