Male Repro Physiology 2 Flashcards

1
Q

What are the 2 main function of the testes?

A

Sperm Production

Testosterone

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2
Q

what is the function of testosterone?

A

Male secondary sexual characteristics

Controls spermatogenesis

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3
Q

What does the hypothalamus produce

A

GnRH

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4
Q

What does GnRH cause the release of?

A

Gonadotropins

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5
Q

What 2 gonadotrophins are produced and from where?

A

FSH and LH

From the anterior pituitary

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6
Q

What is FSH responsible for?

A

Sperm production Spermatogenesis

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7
Q

What s LH responsible for?

A

Controls Leydig cells producing testosterone

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8
Q

What happens when there is too much testosterone?

A

Negative signal to hypothalamus and anterior pituitary

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9
Q

What is the function of inhibin?

A

Negative signal to anterior pituitary

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10
Q

How long is the average cycle spermatogenesis?

A

64 days

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11
Q

When does spermatogenesis start and end?

A

Starts at puberty

It is life-long

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12
Q

What is sperm produced from?

A

Primordial germ cell

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13
Q

What are the 2 stages of sperm development?

A

Spermatocytogenesis

spermiogenesis

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14
Q

What is spermatocytogenesis?

A

Clonal expansion and maturation through mitotic and meiotic division

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15
Q

What is spermiogenesis?

A

Maturation of spermatids into functional sperm cells

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16
Q

How many divisions occur in spermatocytogenesis and what type of division?

A

One mitotic division

two meiotic divisions

17
Q

What are the 2 type of factors that can affect spermatogenesis?

A

Environmental

Medical

18
Q

What are the 2 type of environmental factors?

A

Maternal

Paternal

19
Q

Are maternal factors reversible or irreversible?

A

Irreversible

20
Q

Are paternal factors reversible or irreversible?

A

Reversible

21
Q

What are paternal factors?

A

Smoking
Obesity
Chemical exposure

22
Q

What are the 2 types of medical problems?

A

Pre-testicular

Testicular

23
Q

What are pretesticular problems?

A

Problem with hormonal control

24
Q

What are testicular problems?

A

Problem at the site of production

25
Q

Examples of pretesticular problems

A
Functional-weight 
Intracranial tumour, cysts 
Prolactinoma
Medications- Opiates, steroids
Genetic-Kallmann’s syndrome (deficiency of GnRH
26
Q

Examples of testicular problems

A
Surgery-orchidectomy
STI
Mumps 
Trauma or torsion 
Radio or chemo
Genetic-Kleinfelter’s