Eclampsia Flashcards
What type of condition is pre-eclampsia?
A placental condition
At what stage in the pregnancy does pre-eclampsia normally affect women?
20 weeks gestation
What is pre-eclampsia characterised by?
New onset hypertension
Proteinuria
What is eclampsia?
The onset of seizures in association with pre-eclampsia
In what period does eclampsia mainly occur?
The antepartum period
What are the seizure in eclampsia due to?
Cerebrovascular spasm
What is cerebrovascular spasm due to?
Cerebral haemorrhage
Cerebral oedema
How does Eclampsia present?
- Headache
- High blood pressure
- Hyperreflexia
- Visual changes
- RUQ/epigastric pain
- Papilledema
- Tonic-clonic seizure
What is classed as high blood pressure in eclampsia?
Systolic above 160mmHg
What is first line in the management of eclampsia?
ABC
What is the second step in the management of eclampsia?
Magnesium sulphate
How is Magnesium sulphate administered?
IV bolus
What is the function of magnesium sulphate?
To prevent seizures
To treat seizures once they develop
How long should magnesium sulphate be continued after delivery?
24 hours after delivery
or
24 hours after last seizure
(Whichever one is later)
How does magnesium sulphate work?
Cerebral dilatation and competitively blocks calcium at synaptic nerve endings
What do you need to monitor when on magnesium sulphate?
Respiratory rate
Reflexes
Urine output
What is the antidote to magnesium sulphate?
Calcium gluconate
When should calcium gluconate be administered?
If toxicity from magnesium sulphate develops
What problem can magnesium sulphate cause?
Respiratory depression
What other medical management can be given for eclampsia?
Anti-hypertensives
What anti-hypertensives can be given for elcampsia?
Labetolol
Hydralazine
What are complications of Eclampsia to look for?
HELLP
DIC
Acute respiratory distress
Pulmonary oedema
Fetal hypoxia
What is HELLP syndrome?
Haemolysis
Elevated liver enzymes
Low platelets
What is DIC?
Disseminated Intravascular Coagulation
What would you give to decrease the risk of pre-eclampsia in subsequent pregnancies?
Low dose aspirin from 12 weeks