Polycystic Ovarian Syndrome Flashcards
What is polycystic ovarian syndrome?
Heterogenous endocrine disorder
When does polycystic ovarian syndrome emerge?
Puberty
What type of condition is Polycystic ovarian syndrome?
Complex condition of ovarian dysfunction
How many women of child bearing age are affected by Polycystic Ovarian syndrome?
One fifth (20%)
What hormone imbalances tend to occur in Polycystic Ovarian Dysfunction?
Raised Luteinising Hormone
Insulin resistance (hyperinsulinaemia)
Raised oestrogen
Hyperandrogenism
How does Polycystic Ovarian Syndrome present?
Subfertility
Oligomenorrhea
Hirsutism (hair around face)
Acne
Obesity
Acanthosis nigricans (pigmented skin around neck folds)
How does Polycystic Ovarian Syndrome present?
Subfertility Oligomenorrhea Hirsutism Acne Obesity Acanthosis nigricans
What biochemical investigations are carried out for Polycystic Ovarian Syndrome?
LH:FSH ratio
Total testosterone
Fasting and oral glucose tolerance tests
What does the LH:FSH ratio exclude?
Excludes menopause when the ratio is normal
What LH:FSH ratio suggests Polycystic Ovarian syndrome?
More than 2
What testosterone level would indicate POS?
Normal or slightly raised
Why would you do a fasting and oral glucose tolerance test?
To diagnose insulin resistance
What clinical presentation would indicate insulin resistance in POS?
Acanthosis
nigricans
What imaging would you do in the investigation of POS?
Transabdominal and Transvaginal ultrasound
What would a ultrasound for POS show?
It would show increased ovarian volume and multiple cysts
