Breast Pathology Flashcards
What are Fibroadenomas?
Benign tumours of fibrous and epithelial tissue
What do fibroadenomas arise from?
Lobules
Who is normally affected by fibroadenomas?
Adolescents and young adults
How do fibroadenomas present?
Firm, non-tender mass
How is the fibroadenoma described?
Rounded with smooth edges
Highly mobile
What size do fibroadenomas normally grow to?
Less than 3cm
What might happen if a fibroadenoma is left untreated?
It may regress
Is there a risk of malignancy with fibroadenoma?
No
What investigations would you do for a fibroadenoma?
Triple assessment
What is the management of a fibroadenoma over 3cm?
Surgical excision
What usually happens to fibroadenomas after menopause?
They regress
What type of tumours are lactating adenomas?
Tubular adenomas
What are lactating adenomas
Enlarging masses that start secreting during pregnancy
What is an intraductal papilloma?
Benign papillary tumour
Who do intraductal papilloma’s affect?
Middle aged women
What do intraductal papilloma’s arise from?
Ductal epithelium
How do intraductal papilloma’s normally present?
Bloody discharge from the nipple
How is the mass with intraductal papilloma’s described?
Elongated mass along the length of the lumen
Is there an increased risk of malignancy with intraductal papilloma’s?
No
What is the management of intraductal papilloma’s?
Microdochectomy
What is fat necrosis?
AN inflammatory reaction to adipose tissue damage
Who is more commonly affected by fat necrosis?
Obese women with larger breasts
What are the 3 main causes of fat necrosis?
Physical trauma
Radiotherapy
Breast Surgery
How does fat necrosis normally present?
Firm and round lesion that may develop into a hard, irregular breast lump
What can fat necrosis mimic?
Breast cancer
What may happen to the mass size initially?
The mass size may increase initially
What might you see on a mammography?
Fibrosis
Calcifications
Egg shell
What is the management of fat necrosis?
No intervention is normally required
What is a phyllodes tumour?
Breast cancer of fibroepithelial origin
Who is normally affected by a phyllodes tumour?
Women in their 40’s/50’s
How does a phyllodes tumour normally present?
Smooth, hard, palpable breast mass which can be seen as a smooth bulge under the skin of the breast
How does advanced phyllodes tumour present?
Ulcer on the breast
How does a phyllodes tumour progress?
It can be aggressive and grow to a very large size
Why are phyllodes tumour’s hard to diagnose?
They present similar to fibroadenoma
What is the difference between phyllodes tumour and fibroadenoma?
Fibroadenomas present in younger people and are slower growing
What investigations would you carry out for a phyllodes tumour?
Triple Assessment
What would you see on a mammography of a phyllodes tumour?
Round breast lesion with well-defined edges.
