Pre-eclampsia Flashcards
What type of condition is pre-eclampsia?
Placental condition
What is pre-eclampsia?
Pregnancy induced hypertension associated with organ damage
What is pre-eclampsia a precursor for the development of?
Eclampsia
What are the main characteristic features of pre-eclampsia?
new-onset hypertension
proteinuria
oedema
When does pre-eclampsia occur?
20 weeks gestation
What is the classification of hypertension in pre-eclampsia?
140/90
What are the possible maternal complications of pre-eclampsia?
Eclampsia
Organ failure
Disseminated intravascular coagulation (DIC)
HELLP syndrome
What are the possible fetal complications of pre-eclampsia?
Intrauterine growth restriction
Pre-term delivery
Placental abruption
Neonatal hypoxia
What are high risk factors for pre-eclampsia?
Pre-existing hypertension
Previous hypertension in pregnancy
Existing autoimmune conditions (e.g. systemic lupus erythematosus)
Diabetes
Chronic kidney disease
What are the moderate risk factors for pre-eclampsia?
Older than 40
BMI > 35
More than 10 years since previous pregnancy
Multiple pregnancy
First pregnancy
Family history of pre-eclampsia
What medication can be given to women with ≥ 1 high risk factors or
≥ 2 moderate factors?
Aspirin 75-150mg daily from 12 weeks gestation until the birth
What blood pressure would indicate that a woman should be admitted for observation?
160/110 mmHg
What medical management can be given for pre-eclampsia?
Oral labetolol
When can oral labetolol not be prescribed?
If the patient is asthmatic
What are alternatives to oral labetolol?
Nifedipine
Hydralazine
