Cervical Cancer Flashcards

1
Q

Who does cervical cancer usually affect?

A

Those who are 25-29

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2
Q

What is cervical cancer strongly associated with?

A

Human Papilloma Virus (HPV)

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3
Q

What are the 2 types of cervical cancer?

A

Squamous cell carcinoma

Adenocarcinoma

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4
Q

What is the main type of cervical cancer?

A

Squamous cell carcinoma

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5
Q

What are the main causative strains of HPV?

A

HPV 16 and 18

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6
Q

What are other risk factors of cervical cancer?

A

Smoking
Multiple sexual partners
Immunosuppression

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7
Q

How is cervical cancer usually detected?

A

Routine cervical screening test

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8
Q

What are the main symptoms of cervical cancer?

A

Vaginal discharge

Abnormal vaginal bleeding: postcoital, intermenstrual or postmenopausal bleeding

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9
Q

What are other possible symptoms of cervical cancer?

A
  • Vaginal discomfort
  • Urinary or bowel habit change
  • Suprapubic pain
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10
Q

What might you see on the cervix in someone with cervical cancer?

A

Abnormal red/white patches

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11
Q

What might be felt on examination of someone with cervical cancer?

A

Pelvic bulkiness on PV examination

Mass felt on PR examination

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12
Q

What is the first line investigation for cervical cancer?

A

Colposcopy

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13
Q

What does a colposcopy allow?

A

Visualisation and biopsy of the cervix

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14
Q

What is used for staging in cervical cancer?

A

CT of chest/ abdomen/ pelvis

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15
Q

What lymph nodes can cervical cancer metastasise to?

A

Pelvic lymph nodes

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16
Q

Where does cervical cancer blood spread to?

A

Liver
Lungs
Bone

17
Q

What is 1A confined to?

A

The cervix

18
Q

What size is 1A?

A

Less than 7mm

19
Q

What is 1B confined to?

A

Confined to the cervix

20
Q

What size is 1B?

A

More than 7mm

21
Q

What is 2 staging?

A

Tumour extends beyond the cervix to upper 2/3 of vagina

22
Q

What is the 3rd staging of cervical cancer?

A

Extension of tumour beyond the cervix and pelvic wall

Lower vagina and pelvis

23
Q

What is 4 staging?

A

Extension of tumour beyond the pelvis- Bladder or rectum

24
Q

What is the management of small cervical cancers in stage 1A?

A

Conisation with free margins to maintain fertility

25
Q

What is the management of early stage cancer when trying to maintain fertility?

A

Radical trachelectomy

26
Q

What does a radical trachelectomy involve?

A

Removal of cervix, upper vagina and pelvic lymph nodes

27
Q

What is the management of early stage cancer when not trying to maintain fertility?

A

Laparoscopic hysterectomy and lymphadenectomy

28
Q

What is the management of invasive or infiltrating cervical cancer?

A

Hysterectomy

29
Q

What is a hysterectomy?

A

Removal of the uterus, primary tumour, lymph nodes and upper part of vagina

30
Q

What is the management for cancer that has spread outside the uterus?

A

Chemotherapy

Radiotherapy

31
Q

What is the screening for cervical cancer?

A

Smear test

32
Q

What age of women are called for a smear test?

A

25-64 years of age

33
Q

How often are women called for screening?

A

Every 3 years from 24-49, after this, they’re called every 5 years

34
Q

What is the purpose of screening for cervical cancer?

A

To identify dyskaryostic cells which are pre-cancerous

35
Q

What does screening allow for?

A

It allows for management before the cancer can develop

36
Q

Who is offered a cytological test?

A

Anyone with a positive HPV test

37
Q

What can abnormal results from a cytological test be divided into?

A
  • Borderline
  • Mild dyskaryosis
  • Moderate dyskaryosis
  • Severe dyskaryosis
38
Q

What should someone with an abnormal cytological test be referred for?

A

Colposcopy

39
Q

What is a colposcopy?

A

A procedure used to look at the cervix, the lower part of the womb at the top of the vagina