Chicken Pox in Pregnancy Flashcards

1
Q

What is the cause of chicken pox?

A

Varciella-zoster virus

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2
Q

What is shingles due to?

A

The reactivation of the dormant virus in the dorsal root ganglion

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3
Q

In pregnancy, what can the varicella-zoster cause?

A

Fetal varicella syndrome

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4
Q

How does chicken pox present?

A

Fever
Fatigue
Pruritic maculopapular rash

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5
Q

What is the period of infectivity of chicken pox?

A

48 hours after the rash has started

to 5-7 days when all the lesions have crusted over

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5
Q

What is the period of infectivity of chicken pox?

A

48 hours after the rash has started

to 5-7 days when all the lesions have crusted over

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6
Q

What is the mother 5x more at risk of due to varicella-zoster?

A

Pneumonitis ( inflammation of lung tissue)

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7
Q

What is there also an increased risk of with varicella zoster in pregnancy?

A

Hepatitis

Encephalitis

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8
Q

When during gestation is the main risk of fetal varicella syndrome higher?

A

Before 28 weeks gestation

No risk after 28 weeks

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9
Q

What are features of Fetal Varicella syndrome?

A
Skin scarring 
Eye defects 
Limb hypoplasia 
Microcephaly 
Learning disabilities
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10
Q

What is there no increased risk of with fetal varicella syndrome?

A

Miscarriage

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11
Q

How would shingles be a risk to the fetus?

A

If the mother is exposed in the second or third trimester

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12
Q

What is the first step in the management of chicken pox exposure in pregnancy

A

Take the mother serum IgG to check for varicella antibodies

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13
Q

What is the management if the woman is less than 20 weeks and not immune to varicella?

A

Give varicella-zoster immunoglobulin (VZIG)

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14
Q

For how long is VZIG effective post exposure?

A

Up to 10 days

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15
Q

What is the management if the pregnant woman is more than 20 weeks gestation and not immune to varicella zoster?

A

VZIG or Acyclovir

Give 7 to 14 days post exposure

16
Q

What is the management if the pregnant woman has VZIG?

A

Reassure

17
Q

What does the safety of acyclovir need to balanced against the risk of?

A

Maternal serious chickenpox infection

Fetal varicella risk

18
Q

What is the medical management if the pregnant women is more than 20 weeks and presents within 24 hours of onset of rash?

A

Oral acyclovir

19
Q

What is the medical management if the pregnant women is more than 20 weeks and presents within 24 hours of onset of rash?

A

Acyclovir should be considered with caution

20
Q

What is the management of a pregnant women who present with severe infection?

A

IV acyclovir