VIII- Micro Case Studies

Question 1

steps in HIV diagnosis

Answer 1

1. antigen/antibody immunoassay
2. antibody differentiation immunoassay
3. HIV NAT

Question 2

HIV tests

Answer 2

1. viral p24 antigen- 2nd detection
2. anti-HIV antibody- last detection
3. viral RNA genome- can be detected earliest

Question 3

common opportunistic infections HIV

Answer 3

1. candidiasis thrush or vulvovaginal
2. cervical dysplasia
3. oral hairy leukoplakia
4. herpes zoster and simplex virus
5. idiopathic thrombocytopenic purpura
6. listeriosis
7. progressive multifocal leukoencephalopathy (PML)
8. CMV- disease and retinitis
9. kaposi sarcoma HHV 8
10. burkitts lymphoma EBV

herpes family!!

Question 4

outcomes of CMV in immunosuppressed

Answer 4

retinal lesions with white necrotic tissue

Question 5

clinical features of Thrush

Answer 5

-from C. Albicans = pseudohyphae in germ tube test
-white plaques on tongue and buccal mucosa

Question 6

treatment for active TB

Answer 6

direct observed therapy for 6 months with 2+ antimicrobials

Question 7

Pneumocystis jiroveci presentation

Answer 7

on silver stain looks like helmet, encysted organisms

also called PCP- fever, SOB, bilateral infiltrates
HIV RISK FACTOR