VIII-Learning and Memory Flashcards

1
Q

concept of learning

A

new info is acquired by nervous system to produce adaptive changes in behavior
-associative learning (passive conditioning or operant reinforcement)
-nonassociative (simple, complex imprinting)

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2
Q

major forms of memory

A
  1. short term - including working second/hours
  2. long term- hours/months
  3. long lasting- months/lifetime
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3
Q

brain regions of memory

A
  1. hippocampus
  2. amygdala
  3. temporal cortex
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4
Q

steps of memory processing

A
  1. sensory input acquired = short term mem
  2. short term mem consolidated/translocated to long term by rehearsal
  3. long term retrieved and recalled back to short term
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5
Q

physiologic mechanisms for learning

working memory

A

sustained/high levels of neuron firing during info holding period @prefrontal cortex

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6
Q

PTSD

A

anxiety disorder after witnessing traumatic event
-memory loss, depression, nightmare, suicide

virtual reality helps control emotions in safe environment

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7
Q

acquisition in associative learning

A

new motor behaviors
-associations b/t new stim and existing behaviors
-new associations b/t familiar stim and existing responses

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8
Q

acquisitions in non associative learning

A
  1. habituation - reduced respones to repeatedly exposed non noxious stim
  2. sensitization - inc response to repeatedly exposed stim, strong hedonic valence
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9
Q

concept of memory

A

encoding/storage/retrieval of learning info/interpreted experience
-can forget info that’s only temp useful
-context important for storage and cross referencing

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10
Q

features of working memory

A

-contents from recall of long term or recent event temporarily in mind
-guides behavior/inhibits inapprop actions
-limited capacity so easy to distract
-matures late in dev
-fragile so targeted by aging, stress

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11
Q

types of declarative/explicit long term

A
  1. episodic- recall events in context of time and place relative to past experience
  2. semantic- general knowledge of facts and concepts without reference to time and place

both brought to conscious level via hippocampus, temporal lobe, cortex

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12
Q

types of nondeclarative long term

A
  1. priming > neocortex
  2. procedural > striatum
  3. associative (emotional > amygdala and motor learning>cerebellum)
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13
Q

domains of memory

A
  1. cognitive- problem solving
  2. psychomotor- dance, swim, ski
  3. affective- like something, love, appreciate

not mutually exclusive

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14
Q

synaptic plasticity

A

mechanism of long term potentiation so enduring inc in synaptic efficacy from high freq stim of an afferent pathway

aka functional strengthening of existing synapses + formation of new synapses + activation of silent synapses

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15
Q

memory consolidation

A

newly encoded mems repeatedly reactivated during sleep to drive gradual redistribution to long term storage
-hippocampus and cortex synchronize during slow wave sleep

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16
Q

active forgetting

A
  1. amygdala stores fear memories
  2. prefrontal cortex integrates CS info with context info by hippocampus
  3. PFC inhibits amygdala output to reduce fear for extinction
17
Q

anterograde amnesia

A

inability to form new memories bc defect in consolidation from hippocampus damage
-affects declarative NOT procedural mem

18
Q

retrograde amnesia

A

inability to recall previously stored memories esp more recent memories, older ones are more resistant (temporal quality)
-memory trace still present

ex. concussion

19
Q

agnosia

A

inability to recognize stimuli, commands

20
Q

alzheimers hallmark

A

mem impairment with neuronal loss in hippocampus, cortex, basal forebrain (cholinergic)
-early stage anterograde amnesia > retrograde amnesia
-aphasia, apraxia, agnosia

21
Q

etiology of alzheimers

A

neurofibrillary tangles/tau + senile plaques/beta amyloid

risk factors: age, fam hx, genes (ApoE, APP, PS1,2)

22
Q

korsakoff syndrome

A

lack of thiamine (B1) from chronic alcoholism
-confabulation > anterograde amnesia from damage in mammillary bodies and basal frontal lobes + problems recall

treat with dietary thiamine