Glomeruli Filtration Flashcards
processes of urine production
- glomerular filtration to bowmans capsule
- tubular re-absorption by pertubular caps
- tubular secretion by caps to tubular lumen
renal blood flow
vol of blood delivered to kidneys for excretion, nutrients, affect filtration rate, modify rate of reabsorption, concentrate or dilute urine
glomerular filtration
filtration of plasma from glomerular caps into bowman’s capsule
-starts urine formation
renal plasma flow
vol of blood plasma delivered to kidneys
determinants of glomerular filtration rate
- filtration fraction coefficient
- net filtration force
filtration fraction
fraction of plasma fitlered by glomerular caps
filtration fraction coefficient determiend by
- capillary wall permeability via endothelium, BM, and podocytes
- filtration surface area via mesangial cells
forces favoring filtration
glomerular hydrostatic P
-affected by systemic BP and resistance of arterioles
forces opposing filtration
- glomerular colloid osmotic P
- bowman’s capsule P
affected by arterial plasma colloid osmotic P and filtration fraction
factors that dec GFR
- vasoconstrict afferent arteriole so dec flow into glomerulus
- vasodilate efferent arteriole so more can get out
factors that inc GFR
- vasoconstrict efferent so back up filtrate
- vasodilate afferent so more entering