Unit 4: General Anesthetics

Question 1

L1: Induction rate is ______ as the pulmonary blood flow is increased.

Answer 1

decreased

Question 2

L1: Induction rate is ______ as the solubility of anesthetic in blood is increased.

Answer 2

decreased

Question 3

L1: Minimum Alveolar Concentration is _____ly proportional to the potency and lipid solubility of the agent

Answer 3

inversely

Question 4

L1: More lipid soluble anesthetics have ____er potency.

Answer 4

higher

Question 5

L1: Potency ~ ___

Answer 5

1/MAC

Question 6

L1: Rank the rate of uptake into the following tissues from fastest to slowest: vessel-rich, fat, muscle

Answer 6

Vessel-rich > muscle > fat

Question 7

L1: Rate of increase of partial pressure of anesthetic in alveoli and pulmonary capillaries is proportional to the _______.

Answer 7

ventilation rate

Question 8

L1: Solubility in blood is measured by the ______.

Answer 8

Blood:gas partition coefficient

Question 9

L1: Which anesthetic has MAC >100%?

Answer 9

Nitrous Oxide

Question 10

L2: _______ effect: high % of inspired nitric oxide causes uptake ______ than predicted due to large anesthetic volume

Answer 10

Concentration; faster

Question 11

L2: _______: gases co-administered with nitrous oxide have greater than expected uptake

Answer 11

Second Gas Effect

Question 12

L2: _______: when anesthetic is terminated, large nitric oxide diffusion from the blood to alveoli dilutes alveolar oxygen

Answer 12

Diffusion hypoxia

Question 13

L2: The _______ provides an index of anesthetic potency.

Answer 13

Oil: gas partition coefficient

Question 14

L3: Name the stages of anesthesia.

Answer 14

1. Analgesia, 2. Excitement/Delirium, 3. Surgical Anesthesia, 4. Medullary Paralysis