Unit 1: Congenital/Developmental Disorders Flashcards
L!: What pathologic process? Result from subependymal hemorrhage into the germinal matrix
Perinatal stroke
L1: What pathologic process? Occurs in birth trauma in which the infant’s neck is distorted and carotid arteries are stretched
Perinatal stroke
L1: Which developmental definition/diagnosis? Acquired non-progressive motor disability, with spastic, dyskinetic/athetoid, and ataxic types
Cerebral Palsy
L1: Which developmental definition/diagnosis? Delays or abnormal function in social interaction, language used in social communication, or symbolic/imaginative play
Autism Spectrum Disorder
L1: Which developmental definition/diagnosis? Intellecutal functioning at least two standard deviations below the mean with limitations in at least two adaptive skill areas
Intellectual Disability
L1: Which developmental definition/diagnosis? Restricted repertoire of interests, behaviors, and activities
Autism Spectrum Disorder
L2: ______ fibers: homogenous, eosinophilic, elongated, or globular inclusions with a granular structure containing GFAP
Rosenthal
L2: Antibodies to GFAP are used to visualize _________.
Reactive astrocytes
L2: Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament fiber unique to ______ cells.
astrocyte
L2: How does the distribution of red (Type 1) and white (Type 2) muscle fibers change in denervation atrophy?
Regional segregation
L2: Onion bulbs may form in the process of _________.
Segmental Demyelination
L2: Spinal cord dysfunction from tethering commonly affects the control of _________.
Urinary continence
L2: What pathologic process? Abnormal filaments in perikaryon and neurofibrillary tangles
Alzheimer’s Disease
L2: What pathologic process? Accumulation of CSF within the central canal
Mydromelia
L2: What pathologic process? Bilateral symmetric holes in the brain
Schizencephaly
L2: What pathologic process? Complete failure of primary neurulation
Cranioraschisis totalis
L2: What pathologic process? Complete or partial failure of the prosencephalon to cleave
Holoprosencephaly
L2: What pathologic process? Complex disorder associated with thoracolumbar myelomeningocele
Chiari II Malformation
L2: What pathologic process? CSF-filled cyst that breaks out of the central canal and dissects into the substance of the cord
Syringomelia
L2: What pathologic process? Cystic dilatation of the fourth ventricle, upward displacement of the tentorium, and hydrocephalus
Dandy-Walker Malformation