Unit 2: CNS Tumors

Question 1

L1: What Tumor Grade? Anaplastic Astrocytoma

Answer 1

III

Question 2

L1: What Tumor Grade? Anaplastic Ependymoma

Answer 2

III

Question 3

L1: What Tumor Grade? Anaplastic Oligodendroglioma

Answer 3

III

Question 4

L1: What Tumor Grade? Choroid Plexus Papilloma

Answer 4

I

Question 5

L1: What Tumor Grade? Diffuse Astrocytoma

Answer 5

II

Question 6

L1: What Tumor Grade? Ependymoma

Answer 6

II

Question 7

L1: What Tumor Grade? Ganglioma

Answer 7

I

Question 8

L1: What Tumor Grade? Glioblastoma

Answer 8

IV

Question 9

L1: What Tumor Grade? Medulloblastoma

Answer 9

IV

Question 10

L1: What Tumor Grade? Meningioma

Answer 10

Usually I

Question 11

L1: What Tumor Grade? Oligodendroglioma

Answer 11

II

Question 12

L1: What Tumor Grade? Pilocytic Astrocytoma

Answer 12

I

Question 13

L1: Which tumor frequently spreads through the CSF axis?

Answer 13

Medulloblastoma

Question 14

L2: What genetic marker is commonly involved in medulloblastoma?

Answer 14

Shh

Question 15

L2: What genetic marker is commonly involved in pilocytic astrocytoma?

Answer 15

B-Raf

Question 16

L2: What histologic features in a glioblastoma are not typically seen in anaplastic astrocytoma?

Answer 16

Microvascular proliferation, necrosis

Question 17

L2: What is the most common type of glioma?

Answer 17

Glioblastoma

Question 18

L2: What is the typical age onset of diffuse astrocytoma?

Answer 18

3rd to 5th decades

Question 19

L2: What is the typical age onset of ependymoma?

Answer 19

First two decades of life

Question 20

L2: What is the typical age onset of Glioblastoma?

Answer 20

5th to 6th decades

Question 21

L2: What is the typical age onset of medulloblastoma?

Answer 21

3-8 years

Question 22

L2: What is the typical age onset of meningioma?

Answer 22

older adults

Question 23

L2: What is the typical age onset of oligodrendroglioma?

Answer 23

Adulthood

Question 24

L2: What is the typical age onset of pilocytic astrocytoma?

Answer 24

Childhood

Question 25

L2: What is/are the most common anatomic site(s) for diffuse astrocytoma?

Answer 25

White matter of cerebral hemispheres

Question 26

L2: What is/are the most common anatomic site(s) for ependymoma?

Answer 26

Fourth ventricle

Question 27

L2: What is/are the most common anatomic site(s) for ganglioma?

Answer 27

Temporal lobe

Question 28

L2: What is/are the most common anatomic site(s) for medulloblastoma?

Answer 28

Cerebellar vermis

Question 29

L2: What is/are the most common anatomic site(s) for meningioma?

Answer 29

Adjacent to the dura

Question 30

L2: What is/are the most common anatomic site(s) for oligodendroglioma?

Answer 30

Cerebral hemisphere white matter with penetration of overlying gray cortex

Question 31

L2: Which tumor originates from external granule cell layers?

Answer 31

Medulloblastoma

Question 32

L3: What genetic marker is commonly involved in diffuse astrocytoma?

Answer 32

IDH, TP53 mutation/17p loss

Question 33

L3: What genetic marker is commonly involved in oligodendroglioma?

Answer 33

IDH, 1p/19q LOH

Question 34

L3: What is/are the most common anatomic site(s) for choroid plexus papilloma?

Answer 34

lateral ventricles (children), fourth ventricle (adult)

Question 35

L3: What is/are the most common anatomic site(s) for pilocytic astrocytoma?

Answer 35

Cerebellar hemispheres, optic nerves and chiasm, hypothalamic region