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Neuro > Unit 3: Cerebellum > Flashcards

Unit 3: Cerebellum Flashcards

1
Q

L1: _____ fibers fire when the inferior olivary nucleus detects a discrepancy between planned and actual motor performance

A

Climbing

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2
Q

L1: _____ fibers originate in the _______ and contact only a about a dozen Purkinje fibers

A

Climbing; contralateral inferior olivary nucleus

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3
Q

L1: _____ fibers provide ______ input to granule cells.

A

Mossy; excitatory

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4
Q

L1: Anatomical location of corticocerebellum

A

lateral hemispheres

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5
Q

L1: Cell layer beneath the molecular layer and above the granule cell layer

A

Purkinje fiber layer

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6
Q

L1: Cerebellar fibers decussate _______ (rostral/caudal) to the cerebellum

A

Rostral

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7
Q

L1: Cerebellar lesions can result in ______ tremors.

A

Intention

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8
Q

L1: Cerebellar lesions result in ___-lateral deficits

A

ipsi-

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9
Q

L1: Climbing fiber input results in a _____ spike.

A

complex

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10
Q

L1: Dendrites of Purkinje fibers lie in the _____ layer.

A

molecular

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11
Q

L1: Each ______ cell is contacted by a single _____ fiber.

A

Purkinje; climbing

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12
Q

L1: Input and output of corticocerebellum

A

Cortical regions

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13
Q

L1: Mossy fiber input results in a _____ spike.

A

simple

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14
Q

L1: The ______ acts as a comparator for actual and expected movement

A

inferior olivary nucleus

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15
Q

L1: The major inputs to the cerebellum are carried in the ________.

A

Inferior and middle cerebellar peduncles

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16
Q

L1: The major outputs from the cerebellum are carried in the _______.

A

Superior cerebellar peduncle

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17
Q

L1: What term? Inability of a patient to bring a limb to the desired/required point in space

A

dysmetria

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18
Q

L1: What term? Inability of a patient to execute rapid alternating movements

A

dysdiadochokinesia

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19
Q

L1: What term? Loss of coordination or timing of muscles

A

ataxia

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20
Q

L1: Which anatomical region of the cerebellum does not synapse in the deep nuclei?

A

Flocculonodular lobe

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21
Q

L2: ______ have fibers that project to the ______ layer where the bifurcate into ______ fibers.

A

Granule cells; molecular; parallel

22
Q

L2: ______: inhibitory interneurons scattered in the molecular layer

A

Basket and stellate cells

23
Q

L2: _____-ergic neurons from the _______ supply input to the inferior olivary nucleus

A

GABA; deep cerebellar nuclei

24
Q

L2: Anatomical location of spinocerebellum

A

Vermis and paravermal region

25
Q

L2: Anatomical location of vestibulocerebellum

A

Flocculonodular lobe

26
Q

L2: Basket cells and stellate cells supply _____ input to Purkinje fibers.

A

inhibitory

27
Q

L2: Climbing fiber firing results in activation of Purkinje cells simultaneously with ______, resulting in ________.

A

Parallel fibers; Long-term depression

28
Q

L2: Efferent connections: Lateral hemispheres > _____ nucleus > ______

A

Dentate; contralateral ventrolateral (VL) thalamus to cortex

29
Q

L2: Efferent connections: Paravermal region > _____ nucleus > _________

A

Nucleus interpositus; contralateral red nucleus

30
Q

L2: Firing of the ION climbing fibers occurs when the input from _______ and _______ neurons does not cancel out.

A

GABA-ergic deep cerebellar nuclei, afferent sensory

31
Q

L2: Input and output of vestibulocerebellum

A

vestibular organs; vestibular nucleus

32
Q

L2: Long Term Depression ______ Purkinje fiber response to parallel fiber synapses

A

decreases

33
Q

L2: Mossy and climbing fibers supply _____ input to the deep cerebellar nuclei

A

excitatory

34
Q

L2: Parallel fibers and climbing fibers supply _____ input to Purkinje cells

A

excitatory

35
Q

L2: Purkinje fibers supply _____ input to the deep cerebellar nuclei

A

inhibitory

36
Q

L2: The ______ conveys joint angle calculations to the premotor cortex where calculations between actual and desired location are made

A

parietal cortex

37
Q

L2: The cerebellum can be described as _________ controller.

A

an adaptive feed-forward

38
Q

L2: The deep nuclei receive excitatory input from _______ fibers.

A

mossy and climbing

39
Q

L2: The only output from the cerebellar cortex is via ______ fibers, which supply _____ input to the deep nuclei

A

Purkinje; inhibitory

40
Q

L2: The parietal cortex supplies ______ fibers that synapse on _______ fibers.

A

corticopontine; pontocerebellar mossy

41
Q

L2: The vermal and paravermal regions receive input from the _______.

A

spinal cord

42
Q

L2: Three functional regions of the crerebellum

A

Vestibulocerebellum, spinocerebellum, corticocerebellum

43
Q

L3: Efferent connections: Vermal region > _____ nucleus > __________

A

fastigial; vestibular nucleus, pontine reticular formation

44
Q

L3: Function of the corticocerebellum

A

Initiation, planning, timing

45
Q

L3: Function of the paravermal spinocerebellum

A

Distal Motor control

46
Q

L3: Function of the vermal spinocerebellum

A

Posture, locomotion, gaze (axial)

47
Q

L3: Function of the vestibulocerebellum

A

Balance, eye movement

48
Q

L3: HANDS Tremor

A

hypotonia, ataxia, nystagmus, dysarthria, stance/gait, intention tremor

49
Q

L3: Information from the motor cortices synapses with __________ nuclei and then proceeds to the ______ of the cerebellum.

A

ipsilateral pontine nuclei; contralateral lateral hemispheres

50
Q

L3: Input and output of spinocerebellum

A

spinal afferents; motor control nuclei

Neuro (40 decks)

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